PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9024236-9 1997 Compared to those on the control day, a significant rise in the integrated PRA levels occurred on the first day of nifedipine treatment, with a further rise observed on the eighth day of the treatment in the normotensive subjects (1.1 +/- 0.6, 1.7 +/- 1.2, and 2.5 +/- 1.8 ng/mL.h on the control day and the first and eighth days of treatment, respectively; P < 0.05) and by the eighth day in the hypertensive subjects (2.2 +/- 2.8 and 4.0 +/- 4.1 ng/mL.h; P < 0.05). Nifedipine 115-125 S100 calcium binding protein A6 Homo sapiens 75-78 9024236-12 1997 When individual time points were examined in the normotensive subjects, Aldo/PRA levels were significantly lower on day 8 of nifedipine treatment at 1000, 1200, and 1400 h than corresponding values on the control day. Nifedipine 125-135 S100 calcium binding protein A6 Homo sapiens 77-80 9024236-13 1997 The fall in the Aldo/PRA ratio during nifedipine treatment indicates that the previously reported in vitro inhibition of Aldo biosynthesis in adrenal cells is reproduced in vivo. Nifedipine 38-48 S100 calcium binding protein A6 Homo sapiens 21-24 2765972-5 1989 In 4 elderly women (61-77 yrs), PRA level after nifedipine tended to rise, no such trend was observed for aldosterone. Nifedipine 48-58 S100 calcium binding protein A6 Homo sapiens 32-35