PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7752096-1	1995	The dose-related effects of a single injection of D-amphetamine (AMPH) or methamphetamine (METH) on the mRNA expression of the immediate early gene zif/268 and the opioid peptide preprodynorphin, in rat forebrain, were investigated with quantitative in situ hybridization histochemistry 3 h after injection.	Dextroamphetamine	50-63	early growth response 1	Rattus norvegicus	148-155	
7752096-1	1995	The dose-related effects of a single injection of D-amphetamine (AMPH) or methamphetamine (METH) on the mRNA expression of the immediate early gene zif/268 and the opioid peptide preprodynorphin, in rat forebrain, were investigated with quantitative in situ hybridization histochemistry 3 h after injection.	Dextroamphetamine	65-69	early growth response 1	Rattus norvegicus	148-155	
7752096-4	1995	Dose-dependent induction of zif/268 mRNA also occurred in caudoputamen after injection of AMPH at all doses.	Dextroamphetamine	90-94	early growth response 1	Rattus norvegicus	28-35	
7752096-8	1995	These results demonstrate a clear dose-related responsiveness of zif/268 and preprodynorphin gene expression in cortical and/or striatal neurons that is positively correlated with a dose-dependent motor-stimulating effect of AMPH and METH.	Dextroamphetamine	225-229	early growth response 1	Rattus norvegicus	65-72	
7886627-1	1994	The role of N-methyl-D-aspartate (NMDA) excitatory amino acid receptors in D-amphetamine (AMPH)-induced behavioral changes and increased expression of the nuclear transcription factors, c-fos and zif/268, and preprodynorphin (PPD) mRNA in various regions of rat forebrain was investigated with quantitative in situ hybridization histochemistry.	Dextroamphetamine	75-88	early growth response 1	Rattus norvegicus	196-203	
7886627-1	1994	The role of N-methyl-D-aspartate (NMDA) excitatory amino acid receptors in D-amphetamine (AMPH)-induced behavioral changes and increased expression of the nuclear transcription factors, c-fos and zif/268, and preprodynorphin (PPD) mRNA in various regions of rat forebrain was investigated with quantitative in situ hybridization histochemistry.	Dextroamphetamine	90-94	early growth response 1	Rattus norvegicus	196-203	
7886627-5	1994	attenuated AMPH-induced striatal and cortical expression of zif/268 mRNA and striatal expression of PPD mRNA, without affecting the behavioral alterations induced by AMPH.	Dextroamphetamine	11-15	early growth response 1	Rattus norvegicus	60-67	
7886627-6	1994	A similar, dose-dependent suppression of AMPH-induced zif/268 and PPD mRNA in striatum and cortex was also revealed after systemic administration of (+/-)-3-(2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP) at doses of 5 and 10 mg/kg.	Dextroamphetamine	41-45	early growth response 1	Rattus norvegicus	54-61	
7886627-10	1994	These studies indicate that NMDA receptors mediate, at least in part, activation of zif/268 and PPD gene expression in striatum and sensorimotor cortex by a single injection of AMPH.	Dextroamphetamine	177-181	early growth response 1	Rattus norvegicus	84-91	
7877442-6	1994	However, the AMPH-stimulated increase in PPD and zif/268 mRNA levels in striatum, but not zif/268 mRNA in cortex, was blocked by DNQX pretreatment.	Dextroamphetamine	13-17	early growth response 1	Rattus norvegicus	49-56