PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21683736-0	2011	L-DOPA neurotoxicity is prevented by neuroprotective effects of erythropoietin.	Levodopa	0-6	erythropoietin	Rattus norvegicus	64-78	
21683736-2	2011	Considering the well known neuroprotective effects of erythropoietin (EPO), the inhibitory effects of EPO on L-DOPA neurotoxicity need to be evaluated.	Levodopa	109-115	erythropoietin	Rattus norvegicus	102-105	
21683736-7	2011	Free radicals and hydroxyl radical levels increased by L-DOPA were decreased after combined treatment of L-DOPA and EPO.	Levodopa	55-61	erythropoietin	Rattus norvegicus	105-119	
21683736-10	2011	Pretreatment with LY294002, a phosphatidylinositol 3-kinase inhibitor, prior to combined treatment with EPO and L-DOPA almost completely blocked the protective effects of EPO.	Levodopa	112-118	erythropoietin	Rattus norvegicus	171-174	
21683736-11	2011	These results indicate that EPO can prevent L-DOPA neurotoxicity by activating the PI3K pathway as well as reducing oxidative stress.	Levodopa	44-50	erythropoietin	Rattus norvegicus	28-31