PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34080664-0 2021 (Retracted) miR-133a inhibits cervical cancer growth by targeting EGFR. mir-133a 12-20 epidermal growth factor receptor Homo sapiens 66-70 27933650-7 2017 Compared with the blank and NC groups, the miR-133a mimic and si-EGFR groups exhibited increased cell apoptosis rate but decreased EGFR, p-MEK1/2, and p-ERK1/2 protein expressions; while opposite trend was observed in the miR-133a inhibitors group. mir-133a 43-51 epidermal growth factor receptor Homo sapiens 65-69 35524907-6 2022 The most relevant pathway regulated by miR-133a was ErbB2 signaling, whose main genes involved are EGFR, ERBB2, and RHOA, which are possibly downregulated by miR133a. mir-133a 39-47 epidermal growth factor receptor Homo sapiens 99-103 27933650-7 2017 Compared with the blank and NC groups, the miR-133a mimic and si-EGFR groups exhibited increased cell apoptosis rate but decreased EGFR, p-MEK1/2, and p-ERK1/2 protein expressions; while opposite trend was observed in the miR-133a inhibitors group. mir-133a 43-51 epidermal growth factor receptor Homo sapiens 131-135 27933650-8 2017 Compared with the miR-133a inhibitors group, the miR-133a inhibitors + si-EGFR group presented reduced cell survival rate, EGFR, p-MEK1/2, and p-ERK1/2 protein expressions but increased cell apoptosis rate. mir-133a 49-57 epidermal growth factor receptor Homo sapiens 74-78 27933650-8 2017 Compared with the miR-133a inhibitors group, the miR-133a inhibitors + si-EGFR group presented reduced cell survival rate, EGFR, p-MEK1/2, and p-ERK1/2 protein expressions but increased cell apoptosis rate. mir-133a 49-57 epidermal growth factor receptor Homo sapiens 123-127 27933650-9 2017 These results indicated that miR-133a could inhibit the MEK/ERK pathway to promote cell apoptosis and enhance radio-sensitivity by targeting EGFR in EC. mir-133a 29-37 epidermal growth factor receptor Homo sapiens 141-145 23069713-6 2013 We also discovered that luciferase activity is exclusively decreased by targeting EGFR in hMSCs transfected with miR-133a mimic. mir-133a 113-121 epidermal growth factor receptor Homo sapiens 82-86 24816813-6 2014 MiR-133a can inhibit cell invasiveness and cell growth through suppressing the expressions of IGF-1R, TGFBR1 and EGFR, which then influences the downstream signaling in lung cancer cell lines. mir-133a 0-8 epidermal growth factor receptor Homo sapiens 113-117 26134491-0 2015 miR-133a inhibits cervical cancer growth by targeting EGFR. mir-133a 0-8 epidermal growth factor receptor Homo sapiens 54-58 26134491-9 2015 The epidermal growth factor receptor (EGFR) was confirmed to be a direct target of miR-133a in cervical cancer cells using luciferase assay and western blotting. mir-133a 83-91 epidermal growth factor receptor Homo sapiens 4-36 26134491-9 2015 The epidermal growth factor receptor (EGFR) was confirmed to be a direct target of miR-133a in cervical cancer cells using luciferase assay and western blotting. mir-133a 83-91 epidermal growth factor receptor Homo sapiens 38-42 26134491-10 2015 Restoration of miR-133a inhibited EGFR expression and activated the AKT and ERK signaling pathways. mir-133a 15-23 epidermal growth factor receptor Homo sapiens 34-38 26134491-11 2015 These results showed that miR-133a suppresses cervical cancer growth in vitro and in vivo through targeting EGFR, suggesting that miR-133a can be a potential target for the treatment of cervical cancer. mir-133a 26-34 epidermal growth factor receptor Homo sapiens 108-112 26134491-11 2015 These results showed that miR-133a suppresses cervical cancer growth in vitro and in vivo through targeting EGFR, suggesting that miR-133a can be a potential target for the treatment of cervical cancer. mir-133a 130-138 epidermal growth factor receptor Homo sapiens 108-112 23206218-6 2013 The first evidence was provided that miR-133a and miR-133b may directly target the epidermal growth factor receptor in bladder cancer. mir-133a 37-45 epidermal growth factor receptor Homo sapiens 83-115 23786162-6 2013 A dual luciferase reporter gene assay showed that miR-133a bound to the 3" UTR of EGFR but not a mutated 3" UTR, thereby down-regulating the protein expression level. mir-133a 50-58 epidermal growth factor receptor Homo sapiens 82-86