PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8162600-5 1994 The expression of this Ha-ras is specifically induced by the addition of isopropyl-1-thio-beta-D-galactopyranoside (IPTG), a lactose analogue, to the culture medium. Isopropyl Thiogalactoside 73-114 Harvey rat sarcoma virus oncogene Mus musculus 23-29 8197195-5 1994 When stably transfected cells were induced to express activated Ha-ras by isopropyl beta-D-thiogalactoside administration, there was a marked increase in the number of gross chromosomal aberrations including acentric fragments, multicentric chromosomes, and double minutes, which occurred within the time frame of a single cell cycle from the time of induction. Isopropyl Thiogalactoside 74-106 Harvey rat sarcoma virus oncogene Mus musculus 64-70 8162600-5 1994 The expression of this Ha-ras is specifically induced by the addition of isopropyl-1-thio-beta-D-galactopyranoside (IPTG), a lactose analogue, to the culture medium. Isopropyl Thiogalactoside 116-120 Harvey rat sarcoma virus oncogene Mus musculus 23-29 9022041-2 1997 When grown in medium containing more than 0.1 mM isopropyl beta-D-thiogalactoside (IPTG), the Ha-ras gene was induced up to 20-fold. Isopropyl Thiogalactoside 49-81 Harvey rat sarcoma virus oncogene Mus musculus 94-100 25885317-5 2015 Stable cell lines of human breast cancer (MCF-7-ras) and mouse NIH3T3 fibroblasts (7-4) harboring the inducible Ha-ras (val12) oncogene, which could be induced by isopropylthio-beta-D-galactoside (IPTG), were used to clarify the relationship between Ras and the up-regulated genes. Isopropyl Thiogalactoside 163-195 Harvey rat sarcoma virus oncogene Mus musculus 112-118 25885317-5 2015 Stable cell lines of human breast cancer (MCF-7-ras) and mouse NIH3T3 fibroblasts (7-4) harboring the inducible Ha-ras (val12) oncogene, which could be induced by isopropylthio-beta-D-galactoside (IPTG), were used to clarify the relationship between Ras and the up-regulated genes. Isopropyl Thiogalactoside 197-201 Harvey rat sarcoma virus oncogene Mus musculus 112-118 12618760-4 2003 Our results demonstrate that overexpression of the inducible Ha-ras oncogene by isopropyl-beta-D-thiogalactoside (IPTG) increases the levels of reactive oxygen species (ROS, including O(2*-) and hydrogen peroxide (H(2)O(2))) and GSH in an Ha-ras-transformed NIH/3T3 fibroblast cell line. Isopropyl Thiogalactoside 80-112 Harvey rat sarcoma virus oncogene Mus musculus 61-67 12618760-4 2003 Our results demonstrate that overexpression of the inducible Ha-ras oncogene by isopropyl-beta-D-thiogalactoside (IPTG) increases the levels of reactive oxygen species (ROS, including O(2*-) and hydrogen peroxide (H(2)O(2))) and GSH in an Ha-ras-transformed NIH/3T3 fibroblast cell line. Isopropyl Thiogalactoside 80-112 Harvey rat sarcoma virus oncogene Mus musculus 239-245 12618760-4 2003 Our results demonstrate that overexpression of the inducible Ha-ras oncogene by isopropyl-beta-D-thiogalactoside (IPTG) increases the levels of reactive oxygen species (ROS, including O(2*-) and hydrogen peroxide (H(2)O(2))) and GSH in an Ha-ras-transformed NIH/3T3 fibroblast cell line. Isopropyl Thiogalactoside 114-118 Harvey rat sarcoma virus oncogene Mus musculus 61-67 12618760-4 2003 Our results demonstrate that overexpression of the inducible Ha-ras oncogene by isopropyl-beta-D-thiogalactoside (IPTG) increases the levels of reactive oxygen species (ROS, including O(2*-) and hydrogen peroxide (H(2)O(2))) and GSH in an Ha-ras-transformed NIH/3T3 fibroblast cell line. Isopropyl Thiogalactoside 114-118 Harvey rat sarcoma virus oncogene Mus musculus 239-245 10222151-2 1999 This paper clearly shows that the sensitivity of NIH/3T3 cells to TNF-alpha cytotoxicity positively correlated with the expression level of activated Ha-ras transgene, which was manipulated either positively by isopropyl-beta-d-thiogalactoside (IPTG) induction or negatively by a ribozyme or a dominant negative Ras suppression. Isopropyl Thiogalactoside 211-243 Harvey rat sarcoma virus oncogene Mus musculus 150-156 10222151-2 1999 This paper clearly shows that the sensitivity of NIH/3T3 cells to TNF-alpha cytotoxicity positively correlated with the expression level of activated Ha-ras transgene, which was manipulated either positively by isopropyl-beta-d-thiogalactoside (IPTG) induction or negatively by a ribozyme or a dominant negative Ras suppression. Isopropyl Thiogalactoside 245-249 Harvey rat sarcoma virus oncogene Mus musculus 150-156 9667646-3 1998 We demonstrate that overexpression of activated Ha-ras oncogene by exogenous isopropyl-beta-D-thiogalactoside (IPTG) under serum-depleted conditions can stimulate cell apoptosis. Isopropyl Thiogalactoside 77-109 Harvey rat sarcoma virus oncogene Mus musculus 48-54 9667646-3 1998 We demonstrate that overexpression of activated Ha-ras oncogene by exogenous isopropyl-beta-D-thiogalactoside (IPTG) under serum-depleted conditions can stimulate cell apoptosis. Isopropyl Thiogalactoside 111-115 Harvey rat sarcoma virus oncogene Mus musculus 48-54 16274703-2 2006 Ha-ras overexpression was induced by isopropyl beta-D-thiogalactoside (IPTG). Isopropyl Thiogalactoside 37-69 Harvey rat sarcoma virus oncogene Mus musculus 0-6 16274703-2 2006 Ha-ras overexpression was induced by isopropyl beta-D-thiogalactoside (IPTG). Isopropyl Thiogalactoside 71-75 Harvey rat sarcoma virus oncogene Mus musculus 0-6 9022041-2 1997 When grown in medium containing more than 0.1 mM isopropyl beta-D-thiogalactoside (IPTG), the Ha-ras gene was induced up to 20-fold. Isopropyl Thiogalactoside 83-87 Harvey rat sarcoma virus oncogene Mus musculus 94-100 9022041-5 1997 Ha-ras gene expression in tumors was strongly induced in the presence of IPTG in vivo. Isopropyl Thiogalactoside 73-77 Harvey rat sarcoma virus oncogene Mus musculus 0-6 9022041-6 1997 Induction of Ha-ras gene expression in mice was consistently observed after 48 hr of exposure to drinking water containing IPTG. Isopropyl Thiogalactoside 123-127 Harvey rat sarcoma virus oncogene Mus musculus 13-19 9030247-2 1997 A murine NIH/3T3-derived cell line, designated 2-12, contains an inducible Ha-ras oncogene, which is regulated by the Escherichia coli (E. coli) lac operator/repressor system, and displays a transformed phenotype after isopropyl-beta-D-thiogalactoside induction. Isopropyl Thiogalactoside 219-251 Harvey rat sarcoma virus oncogene Mus musculus 75-81