PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34628369-10	2021	Collectively, our novel findings for first time showed that, Schisandrin B suppressed NLRP3 inflammasome activation-mediated interleukin-1beta (IL-1beta) level and pyroptosis in intestinal epithelial cells of colitis model through the activation of AMPK/Nrf2 dependent signaling-ROS-induced mitochondrial damage, which may be a significant therapeutic approach in the treatment of acute colitis.	schizandrin B	61-74	interleukin 1 beta	Mus musculus	125-142	
29031142-10	2017	The levels of inflammatory mediators TNF-alpha, IL-1beta, and IL-6 in BALF were also inhibited by SchB.	schizandrin B	98-102	interleukin 1 beta	Mus musculus	48-56	
29166724-8	2017	Masson staining results showed that the degree of myocardial fibrosis in MI+ Sch B group was significantly less than that of MI+ vehicle group.Moreover, Sch B could down-regulate some inflammatory cytokines, like NF-kappaB TGF-beta TNF-alpha and IL-1beta, activate Akt-eNOS pathway, upgrade Bcl-2 and downgrade Bax and reduce cell apoptosis as compared with MI+ vehicle group (all P<0.05).	schizandrin B	77-82	interleukin 1 beta	Mus musculus	246-254	
29736208-4	2018	Our experimental results demonstrated that Sch B inhibited production of IL-1beta, TNF-alpha, IL-6 and HMGB1 by LPS-activated RAW264.7 cells.	schizandrin B	43-48	interleukin 1 beta	Mus musculus	73-81	
27733273-5	2016	Gomisin N inhibited LPS-induced expression of mRNAs for inflammation-related genes (inducible nitric oxide synthase (iNOS), cyclooxygenase (COX)-2, interleukin (IL)-1beta, IL-6 and tumor necrosis factor (TNF)-alpha) in BV-2 cells.	schizandrin B	0-9	interleukin 1 beta	Mus musculus	148-170	
26832323-6	2016	In addition, pretreatment with SchB lowered the number of inflammatory cells and pro-inflammatory cytokines including tumor necrosis factor-alpha, interleukin-1beta, and interleukin-6 in BALF.	schizandrin B	31-35	interleukin 1 beta	Mus musculus	147-164