PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27977512-0	2017	Schisandrin B inhibits the proliferation and invasion of glioma cells by regulating the HOTAIR-micoRNA-125a-mTOR pathway.	schizandrin B	0-13	mechanistic target of rapamycin kinase	Homo sapiens	108-112	
26349966-7	2015	RESULTS: Schisandrin B suppressed cell migration and invasion in manner of dose dependent as well as inhibited expression of p-Akt, p-mTOR and MMP-9.	schizandrin B	9-22	mechanistic target of rapamycin kinase	Homo sapiens	134-138	
26349966-8	2015	Activation of PI3K by 740Y-P treatment leaded to upregulation of p-Akt, mTOR and MMP-9; inactivation of mTOR by Rapamycin treatment inhibited expression MMP-9 while activation of mTOR by l-Leucine treatment enhanced MMP-9 expression in Schisandrin B incubated cells.	schizandrin B	236-249	mechanistic target of rapamycin kinase	Homo sapiens	104-108	
26349966-8	2015	Activation of PI3K by 740Y-P treatment leaded to upregulation of p-Akt, mTOR and MMP-9; inactivation of mTOR by Rapamycin treatment inhibited expression MMP-9 while activation of mTOR by l-Leucine treatment enhanced MMP-9 expression in Schisandrin B incubated cells.	schizandrin B	236-249	mechanistic target of rapamycin kinase	Homo sapiens	104-108	
26349966-0	2015	Schisandrin B suppresses glioma cell metastasis mediated by inhibition of mTOR/MMP-9 signal pathway.	schizandrin B	0-13	mechanistic target of rapamycin kinase	Homo sapiens	74-78	
26349966-9	2015	Anti-migration and invasion action of Schisandrin B was also reversed by mTOR activation.	schizandrin B	38-51	mechanistic target of rapamycin kinase	Homo sapiens	73-77	
26349966-10	2015	CONCLUSION: Our findings demonstrate that Schisandrin B can suppress migration and invasion of glioma cell via PI3K/Akt-mTOR-MMP-9 signaling pathway.	schizandrin B	42-55	mechanistic target of rapamycin kinase	Homo sapiens	120-124	
19625493-8	2009	The protein kinase activity of immunoaffinity-purified ATR was dose-dependently decreased by SchB in vitro (IC(50): 7.25 muM), but the inhibitory effect was not observed in ATM, Chk1, PI3K, DNA-PK, and mTOR.	schizandrin B	93-97	mechanistic target of rapamycin kinase	Homo sapiens	202-206	
35405150-6	2022	RESULTS: Sch B simultaneously active autophagy through AMPK/mTOR pathway and decreased the number of lipid droplets in FFA-treated HepG2 cells and MPHs.	schizandrin B	9-14	mechanistic target of rapamycin kinase	Homo sapiens	60-64	
32741948-0	2020	Gomisin N Exerts Anti-liver Cancer Effects and Regulates PI3K-Akt and mTOR-ULK1 Pathways in Vitro.	schizandrin B	0-9	mechanistic target of rapamycin kinase	Homo sapiens	70-74