PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2174491-3 1990 We have previously reported that the peripheral benzodiazepine ligands, Ro5-4864 and PK 11195, modulate prolactin-stimulated mitogenesis in the Nb2 cell(1). Benzodiazepines 48-62 prolactin Rattus norvegicus 104-113 1321364-0 1992 Effects of central and peripheral type benzodiazepine ligands on thyrotropin and prolactin secretion. Benzodiazepines 39-53 prolactin Rattus norvegicus 81-90 1321364-9 1992 The sedating (or agitating in case of FG 7142) effect of high doses of benzodiazepine ligands may contribute to the changes in TSH and PRL levels. Benzodiazepines 71-85 prolactin Rattus norvegicus 135-138 6322044-11 1983 However, the potency of analogues for inhibition of the release of prolactin and TSH following systemic administration indicates that benzodiazepines with affinity for the central subtype of receptors were the most potent. Benzodiazepines 134-149 prolactin Rattus norvegicus 67-76 6320963-1 1984 Benzodiazepines reduce basal and stimulated rat prolactin (PRL) serum levels in vivo. Benzodiazepines 0-15 prolactin Rattus norvegicus 59-62 2994844-15 1985 It is concluded that stress-induced prolactin secretion is regulated by a benzodiazepine-mediated mechanism and that stress-induced renin but not prolactin secretion is mediated in part via beta-receptors. Benzodiazepines 74-88 prolactin Rattus norvegicus 36-45 6287328-0 1982 Benzodiazepine antagonist Ro 15-1788 counteracts the prolactin-lowering effects of other benzodiazepines in rats. Benzodiazepines 0-14 prolactin Rattus norvegicus 53-62 6979001-0 1982 Suppression of prolactin secretion by benzodiazepines in vivo. Benzodiazepines 38-53 prolactin Rattus norvegicus 15-24 6979001-1 1982 Administration of benzodiazepines to male or female rats was observed to inhibit prolactin release. Benzodiazepines 18-33 prolactin Rattus norvegicus 81-90 6979001-2 1982 Basal secretion of prolactin was only slightly suppressed with the highest dose of benzodiazepines; however, the rise in prolactin release following a stimulus was prevented even at low doses (0.1-1 mg/kg). Benzodiazepines 83-98 prolactin Rattus norvegicus 19-28 6979001-3 1982 The benzodiazepine diazepam blocked stress-induced prolactin release and, when given during the critical period of proestrus, the proestrus surge of prolactin. Benzodiazepines 4-18 prolactin Rattus norvegicus 51-60 6979001-3 1982 The benzodiazepine diazepam blocked stress-induced prolactin release and, when given during the critical period of proestrus, the proestrus surge of prolactin. Benzodiazepines 4-18 prolactin Rattus norvegicus 149-158 6979001-5 1982 Inhibition of prolactin release by benzodiazepine was dose related, and inhibition was still evident after repeated diazepam injection. Benzodiazepines 35-49 prolactin Rattus norvegicus 14-23 6979001-6 1982 The potency of three benzodiazepine analogues to inhibit prolactin release correlated with their potency to displace radiolabeled diazepam binding from brain membrane fractions or to induce other biological responses (clonazepam greater than diazepam greater than chlordiazepoxide). Benzodiazepines 21-35 prolactin Rattus norvegicus 57-66 6979001-7 1982 These actions of benzodiazepines on prolactin release are similar to those reported for gamma-aminobutyric acid (GABA). Benzodiazepines 17-32 prolactin Rattus norvegicus 36-45 6287328-1 1982 A number of centrally active benzodiazepines lowered baseline serum prolactin concentrations after oral administration to male rats. Benzodiazepines 29-44 prolactin Rattus norvegicus 68-77 6287328-2 1982 The increase of circulating prolactin levels elicited by oral administration of various neuroleptic agents was also reduced by prior or simultaneous oral administration of several benzodiazepines in a dose-dependent manner. Benzodiazepines 180-195 prolactin Rattus norvegicus 28-37 6287328-3 1982 Since both effects were prevented by simultaneous administration of the benzodiazepine antagonist Ro 15-1788 they are probably mediated by central benzodiazepine receptors which interfere with aminergic mechanisms governing serum prolactin. Benzodiazepines 72-86 prolactin Rattus norvegicus 230-239