PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30680760-5	2019	The chlorine or fluorine substituted position produces a significant effect on the bioactivity and selectivity in AChE inhibition.	Fluorine	16-24	acetylcholinesterase (Cartwright blood group)	Homo sapiens	114-118	
19665386-1	2009	A series of fluorinated oxime compounds was designed and synthesized in order to probe the effect of fluorine substitution on reactivation of inhibited acetylcholinesterase (AChE) by organophosphorus agents.	Fluorine	101-109	acetylcholinesterase (Cartwright blood group)	Homo sapiens	152-172	
19665386-1	2009	A series of fluorinated oxime compounds was designed and synthesized in order to probe the effect of fluorine substitution on reactivation of inhibited acetylcholinesterase (AChE) by organophosphorus agents.	Fluorine	101-109	acetylcholinesterase (Cartwright blood group)	Homo sapiens	174-178	
34862575-0	2021	Fluorine-free synthesis of Ti3C2 MQDs for smartphone-based fluorescent and colorimetric determination of acetylcholinesterase and organophosphorus pesticides.	Fluorine	0-8	acetylcholinesterase (Cartwright blood group)	Homo sapiens	105-125	
4795479-1	1973	Inhibition of acetylcholinesterase using fluorine ions].	Fluorine	41-49	acetylcholinesterase (Cartwright blood group)	Homo sapiens	14-34	
30680760-0	2019	Structure-activity study of fluorine or chlorine-substituted cinnamic acid derivatives with tertiary amine side chain in acetylcholinesterase and butyrylcholinesterase inhibition.	Fluorine	28-36	acetylcholinesterase (Cartwright blood group)	Homo sapiens	121-141	
30680760-1	2019	In this study, a series of new fluorine or chlorine-substituted cinnamic acid derivatives that contain tertiary amine side chain were designed, synthesized, and evaluated in acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibition.	Fluorine	31-39	acetylcholinesterase (Cartwright blood group)	Homo sapiens	174-194	
30680760-1	2019	In this study, a series of new fluorine or chlorine-substituted cinnamic acid derivatives that contain tertiary amine side chain were designed, synthesized, and evaluated in acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibition.	Fluorine	31-39	acetylcholinesterase (Cartwright blood group)	Homo sapiens	196-200	
27914299-7	2017	In the second section, the effect of fluorination on the drug enzyme interactions was evaluated by using two effective methods Based on the molecular docking and density functional theory (DFT) calculations fluorine substitution influenced the Donepezil Acetylcholinesterase interactions.	Fluorine	207-215	acetylcholinesterase (Cartwright blood group)	Homo sapiens	254-274	
27342368-1	2017	An essential biological sensor for acetylcholine (ACh) detection is constructed by immobilizing enzymes, acetylcholinesterase (AChE) and choline oxidase (ChO), on the surface of iron oxide nanoparticles (Fe2O3NPs), poly(3,4-ethylenedioxythiophene) (PEDOT)-reduced graphene oxide (rGO) nanocomposite modified fluorine doped tin oxide (FTO).	Fluorine	308-316	acetylcholinesterase (Cartwright blood group)	Homo sapiens	105-125	
27342368-1	2017	An essential biological sensor for acetylcholine (ACh) detection is constructed by immobilizing enzymes, acetylcholinesterase (AChE) and choline oxidase (ChO), on the surface of iron oxide nanoparticles (Fe2O3NPs), poly(3,4-ethylenedioxythiophene) (PEDOT)-reduced graphene oxide (rGO) nanocomposite modified fluorine doped tin oxide (FTO).	Fluorine	308-316	acetylcholinesterase (Cartwright blood group)	Homo sapiens	127-131