PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33138352-3 2020 To support the bromodomain inhibitor discovery process, here we report the first application of protein-observed fluorine (PrOF) NMR to the tandem bromodomains of BRD4 and BRDT to quantify the selectivity of their interactions with acetylated histones as well as small molecules. Fluorine 113-121 bromodomain containing 4 Homo sapiens 163-167 26158404-0 2015 Dual Screening of BPTF and Brd4 Using Protein-Observed Fluorine NMR Uncovers New Bromodomain Probe Molecules. Fluorine 55-63 bromodomain containing 4 Homo sapiens 27-31 25290579-4 2014 Fluorine labeling only modestly affected the Brd4 structure and function assessed by isothermal titration calorimetry, circular dichroism, and X-ray crystallography. Fluorine 0-8 bromodomain containing 4 Homo sapiens 45-49