PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31159151-7	2019	Sulfate and methyl conjugates were approximately ten-fold stronger inhibitors (IC50 = 0.2-0.6 muM) of 6-mercaptopurine oxidation than allopurinol (IC50 = 7.0 muM), and induced more potent inhibition compared to quercetin (IC50 = 1.4 muM).	Mercaptopurine	102-118	latexin	Homo sapiens	94-97	
8645339-10	1996	In the intravenous 6MP group, 6-methylmercaptopurine, its riboside, and 6-methylmercapto-8-hydroxypurine were detectable in plasma in concentrations of 0.3-2.6 muM (6MP steady state levels: 11.6 muM).	Mercaptopurine	19-22	latexin	Homo sapiens	160-163	
8645339-10	1996	In the intravenous 6MP group, 6-methylmercaptopurine, its riboside, and 6-methylmercapto-8-hydroxypurine were detectable in plasma in concentrations of 0.3-2.6 muM (6MP steady state levels: 11.6 muM).	Mercaptopurine	19-22	latexin	Homo sapiens	195-198	
31646218-6	2019	This unique signature was applied in voltammetric detection of 6-MP in blood serum, human urine, and pharmaceutical formulation (tablet) by a considerable high sensitivity of 0.074, 0.058, and 0.036 muA/muM and a detection limit of 87, 97, and 37 nM, respectively.	Mercaptopurine	63-67	latexin	Homo sapiens	203-206	
31159151-7	2019	Sulfate and methyl conjugates were approximately ten-fold stronger inhibitors (IC50 = 0.2-0.6 muM) of 6-mercaptopurine oxidation than allopurinol (IC50 = 7.0 muM), and induced more potent inhibition compared to quercetin (IC50 = 1.4 muM).	Mercaptopurine	102-118	latexin	Homo sapiens	158-161	
31159151-7	2019	Sulfate and methyl conjugates were approximately ten-fold stronger inhibitors (IC50 = 0.2-0.6 muM) of 6-mercaptopurine oxidation than allopurinol (IC50 = 7.0 muM), and induced more potent inhibition compared to quercetin (IC50 = 1.4 muM).	Mercaptopurine	102-118	latexin	Homo sapiens	158-161	
30774864-3	2019	We have previously reported in vitro that the oxidative metabolites of 6TP, specifically 6-thiouric acid (6TU, K i 7 muM), are potent inhibitors of UDP-glucose dehydrogenase (UDPGDH), an enzyme that is responsible for the formation of UDP-glucuronic acid (UDPGA), an essential substrate that is used in detoxification processes in the liver.	Mercaptopurine	71-74	latexin	Homo sapiens	117-120	
29283382-8	2017	The inhibitory constant of mercaptopurine (16 muM) was comparable to that of the well-known inhibitor kojic acid (13 muM).	Mercaptopurine	27-41	latexin	Homo sapiens	46-49	
29283382-8	2017	The inhibitory constant of mercaptopurine (16 muM) was comparable to that of the well-known inhibitor kojic acid (13 muM).	Mercaptopurine	27-41	latexin	Homo sapiens	117-120