PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17493759-1	2007	Glutathione transferases (GSTs) catalyze the bioactivation of the thiopurine prodrugs azathioprine, cis-6-(2-acetylvinylthio)purine (cAVTP) and trans-6-(2-acetylvinylthio)guanine (tAVTG), thereby releasing the antimetabolites 6-mercaptopurine and 6-thioguanine.	Mercaptopurine	226-242	glutathione S-transferase kappa 1	Homo sapiens	26-30	
26935390-7	2016	Thiopurines are catabolized in the liver by xanthine oxidase, with potential production of reactive oxidative species and azathioprine is converted into mercaptopurine by a reaction with reduced glutathione, that, in some tissues, may be facilitated by glutathione- S-transferase (GST).	Mercaptopurine	153-167	glutathione S-transferase kappa 1	Homo sapiens	253-279	
26935390-7	2016	Thiopurines are catabolized in the liver by xanthine oxidase, with potential production of reactive oxidative species and azathioprine is converted into mercaptopurine by a reaction with reduced glutathione, that, in some tissues, may be facilitated by glutathione- S-transferase (GST).	Mercaptopurine	153-167	glutathione S-transferase kappa 1	Homo sapiens	281-284	
26455313-0	2015	A SERS protocol as a potential tool to access 6-mercaptopurine release accelerated by glutathione-S-transferase.	Mercaptopurine	46-62	glutathione S-transferase kappa 1	Homo sapiens	86-111	
26455313-2	2015	In this work, we have developed a SERS technique to monitor the absorbance behaviour of 6-mercaptopurine (6-MP) and its glutathione-S-transferase (GST)-accelerated glutathione (GSH)-triggered release behaviour on the surface of gold nanoflowers (GNFs), using the GNFs as excellent SERS substrates.	Mercaptopurine	88-104	glutathione S-transferase kappa 1	Homo sapiens	147-150	
26455313-2	2015	In this work, we have developed a SERS technique to monitor the absorbance behaviour of 6-mercaptopurine (6-MP) and its glutathione-S-transferase (GST)-accelerated glutathione (GSH)-triggered release behaviour on the surface of gold nanoflowers (GNFs), using the GNFs as excellent SERS substrates.	Mercaptopurine	106-110	glutathione S-transferase kappa 1	Homo sapiens	120-145	
26455313-5	2015	We speculated that GST catalyzes nucleophilic GSH to competitively bind with the electrophilic substance 6-MP.	Mercaptopurine	105-109	glutathione S-transferase kappa 1	Homo sapiens	19-22