PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26481311-7 2016 The integrity of this partnership may be clinically relevant, because hCNT3 may be responsible for the translocation of thiopurines, such as 6-mercaptopurine, a front-line treatment in inflammatory bowel disease. Mercaptopurine 141-157 solute carrier family 28 member 3 Homo sapiens 70-75 21723252-1 2011 Exposure of MOLT4 human T-cell leukemia cells to 6-Mercaptopurine (6-MP) and 6-Thioguanine (6-TG) resulted in acquired resistance associated with attenuated expression of the genes encoding concentrative nucleoside transporter 3 (CNT3) and equilibrative nucleoside transporter 2 (ENT2). Mercaptopurine 49-65 solute carrier family 28 member 3 Homo sapiens 190-228 23934611-7 2013 We also applied the models to pharmacogenomic studies for the drugs gemcitabine and 6-mercaptopurine and found that the diagonal degree model identified an association between 6-mercaptopurine response and expression of the gene SLC28A3, which was not detectable using the model including no pathway information. Mercaptopurine 84-100 solute carrier family 28 member 3 Homo sapiens 229-236 23934611-7 2013 We also applied the models to pharmacogenomic studies for the drugs gemcitabine and 6-mercaptopurine and found that the diagonal degree model identified an association between 6-mercaptopurine response and expression of the gene SLC28A3, which was not detectable using the model including no pathway information. Mercaptopurine 176-192 solute carrier family 28 member 3 Homo sapiens 229-236 21723252-1 2011 Exposure of MOLT4 human T-cell leukemia cells to 6-Mercaptopurine (6-MP) and 6-Thioguanine (6-TG) resulted in acquired resistance associated with attenuated expression of the genes encoding concentrative nucleoside transporter 3 (CNT3) and equilibrative nucleoside transporter 2 (ENT2). Mercaptopurine 49-65 solute carrier family 28 member 3 Homo sapiens 230-234 21723252-1 2011 Exposure of MOLT4 human T-cell leukemia cells to 6-Mercaptopurine (6-MP) and 6-Thioguanine (6-TG) resulted in acquired resistance associated with attenuated expression of the genes encoding concentrative nucleoside transporter 3 (CNT3) and equilibrative nucleoside transporter 2 (ENT2). Mercaptopurine 67-71 solute carrier family 28 member 3 Homo sapiens 190-228 21723252-1 2011 Exposure of MOLT4 human T-cell leukemia cells to 6-Mercaptopurine (6-MP) and 6-Thioguanine (6-TG) resulted in acquired resistance associated with attenuated expression of the genes encoding concentrative nucleoside transporter 3 (CNT3) and equilibrative nucleoside transporter 2 (ENT2). Mercaptopurine 67-71 solute carrier family 28 member 3 Homo sapiens 230-234 16530731-8 2006 Taken together these results show that CNT3 and ENT2 play a key role in the transport of 6-MP and 6-TG by leukemia cells. Mercaptopurine 89-93 solute carrier family 28 member 3 Homo sapiens 39-43