PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34538494-11	2021	In vitro, at the early stages of incubation, treatment with BHB upregulated abundance of phosphorylated of IRE1alpha, PERK, and the cleavage of ATF6, as well as several unfolded protein response genes (X-box-binding protein-1 (XBP1), 78 kDa glucose-regulated protein (GRP78), and C/EBP homologous protein (CHOP)).	3-Hydroxybutyric Acid	60-63	heat shock protein family A (Hsp70) member 5	Bos taurus	234-266	
34538494-12	2021	Furthermore, in response to increasing doses of BHB, the phosphorylation level of PERK, IRE1alpha, and the cleavage of ATF6, and the abundance of XBP1, GRP78, and CHOP increased.	3-Hydroxybutyric Acid	48-51	heat shock protein family A (Hsp70) member 5	Bos taurus	152-157	
34538494-11	2021	In vitro, at the early stages of incubation, treatment with BHB upregulated abundance of phosphorylated of IRE1alpha, PERK, and the cleavage of ATF6, as well as several unfolded protein response genes (X-box-binding protein-1 (XBP1), 78 kDa glucose-regulated protein (GRP78), and C/EBP homologous protein (CHOP)).	3-Hydroxybutyric Acid	60-63	heat shock protein family A (Hsp70) member 5	Bos taurus	268-273	
34001360-11	2021	Overexpression of GRP78 attenuated both BHB-induced ER stress and the ensuing cellular damage, suggesting that hepatocyte damage caused by excessive BHB can be mediated via enhanced ER stress.	3-Hydroxybutyric Acid	40-43	heat shock protein family A (Hsp70) member 5	Bos taurus	18-23	
34001360-11	2021	Overexpression of GRP78 attenuated both BHB-induced ER stress and the ensuing cellular damage, suggesting that hepatocyte damage caused by excessive BHB can be mediated via enhanced ER stress.	3-Hydroxybutyric Acid	149-152	heat shock protein family A (Hsp70) member 5	Bos taurus	18-23