PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32746652-0 2020 Functionality study of chalcone-hydroxypyridinone hybrids as tyrosinase inhibitors and influence on anti-tyrosinase activity. 1-hydroxy-2(1H)-pyridinone 32-49 tyrosinase Homo sapiens 61-71 32746652-0 2020 Functionality study of chalcone-hydroxypyridinone hybrids as tyrosinase inhibitors and influence on anti-tyrosinase activity. 1-hydroxy-2(1H)-pyridinone 32-49 tyrosinase Homo sapiens 105-115 32746652-1 2020 In an attempt to synthesise new tyrosinase inhibitors, we designed and synthesised a series of chalcone-hydroxypyridinone hybrids as potential tyrosinase inhibitors adopting strategic modifications of kojic acid. 1-hydroxy-2(1H)-pyridinone 104-121 tyrosinase Homo sapiens 32-42 32746652-1 2020 In an attempt to synthesise new tyrosinase inhibitors, we designed and synthesised a series of chalcone-hydroxypyridinone hybrids as potential tyrosinase inhibitors adopting strategic modifications of kojic acid. 1-hydroxy-2(1H)-pyridinone 104-121 tyrosinase Homo sapiens 143-153 27185329-0 2016 Design and synthesis of novel hydroxypyridinone derivatives as potential tyrosinase inhibitors. 1-hydroxy-2(1H)-pyridinone 30-47 tyrosinase Homo sapiens 73-83 27185329-1 2016 Two groups of novel hydroxypyridinone derivatives 6(a-e) and 12(a-c), were designed as potential tyrosinase inhibitors, and synthesized using kojic acid as a starting material. 1-hydroxy-2(1H)-pyridinone 20-37 tyrosinase Homo sapiens 97-107