PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29596834-3 2018 Here, we show that AZD5153 dose-dependently inhibited survival, proliferation and cell cycle progression in TPC-1 cells and primary human thyroid carcinoma cells. AZD5153 19-26 two pore segment channel 1 Homo sapiens 108-113 29596834-5 2018 AZD5153 induced caspase-3/-9 and apoptosis activation in TPC-1 cells and primary cancer cells. AZD5153 0-7 two pore segment channel 1 Homo sapiens 57-62 29596834-8 2018 BRD4-regulated proteins, including c-Myc, Bcl-2 and cyclin D1, were significantly downregulated following AZD5153 treatment in TPC-1 and primary cancer cells. AZD5153 106-113 two pore segment channel 1 Homo sapiens 127-132