PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20600799-1 2010 A series of bis-pyridinium oximes connected by methoxy alkane linkers were synthesized and their in vitro reactivation efficacy was evaluated against sarin-inhibited human AChE, and data were compared with 2-PAM and obidoxime. bis-pyridinium oximes 12-33 acetylcholinesterase (Cartwright blood group) Homo sapiens 172-176 20688148-0 2011 In vitro reactivation of sarin-inhibited human acetylcholinesterase (AChE) by bis-pyridinium oximes connected by xylene linkers. bis-pyridinium oximes 78-99 acetylcholinesterase (Cartwright blood group) Homo sapiens 69-73 20688148-1 2011 A series of bis-pyridinium oximes connected by xylene linkers were synthesized and their in vitro reactivation potential was evaluated against human acetylcholinesterase (hAChE) inhibited by nerve agent sarin and the data were compared with 2-PAM and obidoxime. bis-pyridinium oximes 12-33 acetylcholinesterase (Cartwright blood group) Homo sapiens 171-176 18396353-0 2009 Synthesis and evaluation of novel bis-pyridinium oximes as reactivators of DFP-inhibited acetylcholinesterase. bis-pyridinium oximes 34-55 acetylcholinesterase (Cartwright blood group) Homo sapiens 89-109 18396353-1 2009 A series of novel bis-pyridinium oximes connected by bis-methoxymethyl benzene, 1,4-bis-methoxymethyl (cis)-but-2-ene and 1,4-bis-methoxymethyl but-2-yne linkers were synthesized and their in vitro reactivation efficacy was evaluated against diisopropyl phosphorofluoridate (DFP) inhibited acetylcholinesterase (AChE) and compared with the established antidote 2-PAM and obidoxime. bis-pyridinium oximes 18-39 acetylcholinesterase (Cartwright blood group) Homo sapiens 290-310 18396353-1 2009 A series of novel bis-pyridinium oximes connected by bis-methoxymethyl benzene, 1,4-bis-methoxymethyl (cis)-but-2-ene and 1,4-bis-methoxymethyl but-2-yne linkers were synthesized and their in vitro reactivation efficacy was evaluated against diisopropyl phosphorofluoridate (DFP) inhibited acetylcholinesterase (AChE) and compared with the established antidote 2-PAM and obidoxime. bis-pyridinium oximes 18-39 acetylcholinesterase (Cartwright blood group) Homo sapiens 312-316 18565503-5 2008 The reactivation potencies of the bis-pyridinium oximes connected with a (CH(2))(n) linker between the two quaternary nitrogen atoms were evaluated with housefly (HF) AChE inhibited by diisopropyl fluorophosphates (DFP) and by paraoxon. bis-pyridinium oximes 34-55 acetylcholinesterase (Cartwright blood group) Homo sapiens 167-171