PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19557827-7 2009 Consistent with an important role of inflammatory responses in AD, we identified progranulin (mouse Grn; human GRN) as one of the top ten up-regulated molecules in Tg2576 ( approximately 8-fold increased) and APPPS1 ( approximately 2-fold increased) mice compared to littermate controls, and among the eight significantly up-regulated molecules common to both mouse models. tg2576 164-170 granulin precursor Homo sapiens 111-114