PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9681236-0	1998	Severe bactrim-induced neutropenia with reversal of CD4+/CD8+ lymphocyte ratio: response to recombinant human granulocyte-colony stimulating factor (R-metHUG-CSF).	Trimethoprim, Sulfamethoxazole Drug Combination	7-14	CD8a molecule	Homo sapiens	57-60	
9681236-1	1998	A patient presented with severe bactrim-induced neutropenia with a reversed CD4+/CD8+ lymphocyte ratio.	Trimethoprim, Sulfamethoxazole Drug Combination	32-39	CD8a molecule	Homo sapiens	81-84	
9425690-12	1997	However, at very low T4 counts, especially those less than 25/microliter, and at a CD4/CD8 ratio of less than 0.10, the probability of reactions to trimethoprim-sulphamethoxazole (TMP-SMZ) is decreased in late-stage HIV-1 patients.	Trimethoprim, Sulfamethoxazole Drug Combination	148-178	CD8a molecule	Homo sapiens	87-90	
9425690-12	1997	However, at very low T4 counts, especially those less than 25/microliter, and at a CD4/CD8 ratio of less than 0.10, the probability of reactions to trimethoprim-sulphamethoxazole (TMP-SMZ) is decreased in late-stage HIV-1 patients.	Trimethoprim, Sulfamethoxazole Drug Combination	180-187	CD8a molecule	Homo sapiens	87-90	
9126010-12	1997	CONCLUSIONS: The efficacy of desensitization with sulfamethoxazole-trimethoprim was confirmed; this desensitization procedure was more often successful in patients with lower CD4+ cell percentages and CD4+/CD8+ ratios.	Trimethoprim, Sulfamethoxazole Drug Combination	50-79	CD8a molecule	Homo sapiens	206-209