PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8703954-9 1996 This disruption blocks or markedly reduces the binding of choriocarcinoma nuclear factors to the PLAP promoter, leading to a reduction in expression and a loss of butyrate response. Butyrates 163-171 alkaline phosphatase, placental Homo sapiens 97-101 19003149-3 1999 GPI-anchored ALP derived from colon (SW1222 and SW1116) and stomach (MKN-45 and MKN-1) cancer cell lines was heat-stable with and without exposure to butyrate, but GPI-anchored ALP derived from lung cancer cell lines (PC-6, PC13, PC-14, WI26VA4, and WI38VA13) showed a variety of heat stabilities, depending on cell line, butyrate exposure, and SV40 transformation. Butyrates 150-158 alkaline phosphatase, placental Homo sapiens 13-16 19003149-3 1999 GPI-anchored ALP derived from colon (SW1222 and SW1116) and stomach (MKN-45 and MKN-1) cancer cell lines was heat-stable with and without exposure to butyrate, but GPI-anchored ALP derived from lung cancer cell lines (PC-6, PC13, PC-14, WI26VA4, and WI38VA13) showed a variety of heat stabilities, depending on cell line, butyrate exposure, and SV40 transformation. Butyrates 322-330 alkaline phosphatase, placental Homo sapiens 13-16 10029297-1 1999 BACKGROUND AND AIMS: Butyrate, a natural product of colonic bacterial flora, has been reported to increase the activities of a number of enzymes, including alkaline phosphatase, (ALP) in several cancer cell lines. Butyrates 21-29 alkaline phosphatase, placental Homo sapiens 179-182 10029297-2 1999 However, butyrate-induced ALP gene expression in human hepatoma cells has not been previously demonstrated. Butyrates 9-17 alkaline phosphatase, placental Homo sapiens 26-29 10029297-10 1999 CONCLUSION: Butyrate, at a concentration relevant to the normal physiology of the liver, causes augmented expression of ALP mRNA in HepG2 cells. Butyrates 12-20 alkaline phosphatase, placental Homo sapiens 120-123 16465285-4 1997 Butyrate induced cell death is preceded by the induction of two markers of colonic differentiation--alkaline phosphatase (ALP) activity and E-cadherin protein expression. Butyrates 0-8 alkaline phosphatase, placental Homo sapiens 83-120 16465285-4 1997 Butyrate induced cell death is preceded by the induction of two markers of colonic differentiation--alkaline phosphatase (ALP) activity and E-cadherin protein expression. Butyrates 0-8 alkaline phosphatase, placental Homo sapiens 122-125 2745460-10 1989 The isolation and characterization of germ cell ALP cDNA clones from a butyrate-treated choriocarcinoma cDNA library showed that the germ cell ALP mRNA is 2487 bases in length and exon XI of this gene is 1135 base pairs long. Butyrates 71-79 alkaline phosphatase, placental Homo sapiens 48-51 2745460-10 1989 The isolation and characterization of germ cell ALP cDNA clones from a butyrate-treated choriocarcinoma cDNA library showed that the germ cell ALP mRNA is 2487 bases in length and exon XI of this gene is 1135 base pairs long. Butyrates 71-79 alkaline phosphatase, placental Homo sapiens 143-146 2444242-0 1987 Modulation of placental alkaline phosphatase activity and cytokeratins in human HN-1 cells by butyrate, retinoic acid, catecholamines and histamine. Butyrates 94-102 alkaline phosphatase, placental Homo sapiens 14-44 2444242-9 1987 PLAP activity could be modulated by a concerted action of either butyrate plus retinoic acid or butyrate plus catecholamines or histamine, indicating a possible role for PLAP in tumour cell proliferation. Butyrates 65-73 alkaline phosphatase, placental Homo sapiens 0-4 2444242-9 1987 PLAP activity could be modulated by a concerted action of either butyrate plus retinoic acid or butyrate plus catecholamines or histamine, indicating a possible role for PLAP in tumour cell proliferation. Butyrates 96-104 alkaline phosphatase, placental Homo sapiens 0-4 2444242-3 1987 Butyrate enhanced PLAP activity in a time related manner in contrast to retinoic acid, which had no significant effect. Butyrates 0-8 alkaline phosphatase, placental Homo sapiens 18-22 2444242-4 1987 However, retinoic acid inhibited the efficacy of butyrate to induce PLAP activity. Butyrates 49-57 alkaline phosphatase, placental Homo sapiens 68-72 2444242-5 1987 A synergistic enhancement of PLAP activity was demonstrated after treatment of butyrate pretreated cells with catecholamines or histamine. Butyrates 79-87 alkaline phosphatase, placental Homo sapiens 29-33 30562925-16 2018 Exposure to butyrate (2-4 mM) for 3 days markedly stimulated osteonectin secretion and ALP activity. Butyrates 12-20 alkaline phosphatase, placental Homo sapiens 87-90 30562925-18 2018 However, lower concentrations of butyrate (1-4 mM) may stimulate ALP, osteonectin and OPG. Butyrates 33-41 alkaline phosphatase, placental Homo sapiens 65-68 6699450-0 1984 [Modulation of alkaline phosphatase by butyrate and prednisolone in uterine cervical cancer cell line (SKG-III)]. Butyrates 39-47 alkaline phosphatase, placental Homo sapiens 15-35 6604031-4 1983 These data suggested that such oncotrophoblastic proteins as early placental ALP, beta-hCG and SP1 were concordantly modulated by butyrate and prednisolone. Butyrates 130-138 alkaline phosphatase, placental Homo sapiens 77-80