PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16155367-9 2005 The two new PPAR-gamma agonists and 15d-PGJ2 also inhibited TNF-alpha-induced interleukin-6 (IL-6) and monocyte chemoattractant protein-1 (MCP-1) production in supernatants of TNF-alpha-stimulated ECs, whereas ciglitazone and DIM-C-pPhCH(3) did not decrease TNF-alpha-induced expression of these two proteins. ciglitazone 210-221 C-C motif chemokine ligand 2 Homo sapiens 139-144 18242157-11 2008 15d-PGJ2 and ciglitazone blocked the induction of MCP-1 by TNF-alpha. ciglitazone 13-24 C-C motif chemokine ligand 2 Homo sapiens 50-55 18242157-12 2008 Moreover, the addition of MCP-1 rescued the inhibition of TRAP-positive multinucleated cell (TRAP-MNCs) formation by 15d-PGJ2 and ciglitazone, although generated TRAP-MNCs had no capacity to resorb dentin slices. ciglitazone 130-141 C-C motif chemokine ligand 2 Homo sapiens 26-31 18242157-13 2008 Our data demonstrate that 15d-PGJ2 and ciglitazone down-regulate TNF-alpha-mediated osteoclast differentiation in human cells, in part via suppression of the action of MCP-1. ciglitazone 39-50 C-C motif chemokine ligand 2 Homo sapiens 168-173 15659119-4 2005 PPARgamma activators (ciglitazone 30 micromol/L and troglitazone 10 micromol/L) depressed the Hcy-induced MCP-1 production but not IL-8 production in the cultured whole blood. ciglitazone 22-33 C-C motif chemokine ligand 2 Homo sapiens 106-111