PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33705529-6 2022 The presence of cardiomyocyte MPO was associated with higher chlorination and peroxidation activity, increased levels of 3-chlorotyrosine-modified cardiac myosin binding protein-C (MYBPC3), attenuated phosphorylation of MYBPC3 at Ser-282, perturbed calcium signalling, and impaired cardiomyocyte relaxation. 3-chlorotyrosine 121-137 myosin binding protein C3 Homo sapiens 181-187 33705529-7 2022 Interestingly, treatment with the MPO inhibitor, AZD5904, reduced 3-chlorotyrosine-modified MYBPC3 levels, restored MYBPC3 phosphorylation, and alleviated the calcium signalling and relaxation defects. 3-chlorotyrosine 66-82 myosin binding protein C3 Homo sapiens 92-98