PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29069785-5 2017 In addition, [10]-gingerol is well tolerated in vivo, induces a marked increase in caspase-3 activation and inhibits orthotopic tumour growth in a syngeneic mouse model of spontaneous breast cancer metastasis. gingerol 18-26 caspase 3 Mus musculus 83-92 32438504-9 2020 Further, [6]-gingerol improved ISO-induced morphological pathologies, reduced the expression of TNF-alpha, IL-6, c-fos, c-jun, Bax, Caspase-3, TLR4, NF-kappaB, p38, p-p38, ERK1/2, p-ERK1/2, JNK, and p-JNK, and increased Bcl-2 protein expression. gingerol 9-21 caspase 3 Mus musculus 132-141 18030663-6 2007 Results of western blot analysis showed that [6]-gingerol upregulated the testosterone depleted levels of p53 in mouse prostate and upregulated its downstream regulator Bax and further activated Caspase-9 and Caspase-3 in both LNCaP cells and in mouse prostate. gingerol 45-57 caspase 3 Mus musculus 209-218