PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32438504-9 2020 Further, [6]-gingerol improved ISO-induced morphological pathologies, reduced the expression of TNF-alpha, IL-6, c-fos, c-jun, Bax, Caspase-3, TLR4, NF-kappaB, p38, p-p38, ERK1/2, p-ERK1/2, JNK, and p-JNK, and increased Bcl-2 protein expression. gingerol 9-21 interleukin 6 Mus musculus 107-111 34896967-10 2022 Here inhibition mechanism of 6-gingerol is demonstrated on excessive hypertrophy and hyperplasia of adipocytes in white adipose tissue (WAT), which may be related to the regulation of adipocytokines, such as PPARgamma, C/EBPalpha, FABP4 and adiponectin, and the TLR3/IL-6/JAK1/STAT3 axis. gingerol 29-39 interleukin 6 Mus musculus 267-271 32395486-9 2020 Furthermore, 6-gingerol was found to inhibit the increase of mRNA levels and serum and bowel levels of IL-6 and IL-17 induced by DSS, which is similar with mesalazine. gingerol 13-23 interleukin 6 Mus musculus 103-107 27525509-4 2017 The expression of TNFalpha, monocyte chemotactic protein-1, interleukin-1beta, and interleukin-6 were decreased in the coculture insert system using fully differentiated 3T3-L1 cells with RAW 264.7 macrophages treated with 6-gingerol. gingerol 223-233 interleukin 6 Mus musculus 83-96 29508185-11 2018 In addition, gingerol also observably inhibited LPS-induced TNF-alpha, IL-1beta, IL-6, and PGE2 (p < 0.01) expression and secretion in a dose-dependent manner. gingerol 13-21 interleukin 6 Mus musculus 81-85 29508185-12 2018 At the genetic level, after the intervention of gingerol, mRNA transcriptions of iNOS, COX-2, IL-6, and IL-1beta were all decreased. gingerol 48-56 interleukin 6 Mus musculus 94-98 22285432-7 2012 The over-expression of TNFalpha and IL6 in iAs intoxicated mice was down-regulated by [6]-gingerol treatment. gingerol 90-98 interleukin 6 Mus musculus 36-39