PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35347963-9	2022	Additionally, 6-gingerol at a high dose significantly increased the protein and mRNA expression of APN, AdipoR1, PGC-1alpha, and PI3 K in eWAT, elevated the relative expression of p-AMPK~(Thr172) and p-Akt~(Ser 473), reduced the protein and mRNA expression of TNF-alpha, IL-1, and IL-6 in eWAT, and decreased the relative expression of p-JNK1 and p-JNK2.	gingerol	14-24	alanyl aminopeptidase, membrane	Rattus norvegicus	99-102	
35347963-10	2022	This study reveals that 6-gingerol can improve insulin sensitivity of adipose tissues in aging rats with glycolipid metabolism disorders, and this effect is presumedly achieved by enhancing the PI3 K/Akt signaling pathway, inhibiting adipose tissue inflammation, increasing APN synthesis, enhancing AdipoR1 expression, and activating its downstream AMPK/PGC-1alpha signaling pathway.	gingerol	24-34	alanyl aminopeptidase, membrane	Rattus norvegicus	274-277