PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25148824-0	2015	[10]-Gingerol induces mitochondrial apoptosis through activation of MAPK pathway in HCT116 human colon cancer cells.	gingerol	5-13	mitogen-activated protein kinase 1	Homo sapiens	68-72	
25148824-5	2015	Moreover, [10]-gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, c-Jun N-terminal kinase (JNK), p38 MAPK (p38), and extracellular signal-regulated kinase (ERK).	gingerol	15-23	mitogen-activated protein kinase 1	Homo sapiens	184-221	
25148824-5	2015	Moreover, [10]-gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, c-Jun N-terminal kinase (JNK), p38 MAPK (p38), and extracellular signal-regulated kinase (ERK).	gingerol	15-23	mitogen-activated protein kinase 1	Homo sapiens	223-226	
24204396-0	2013	[6]-Gingerol Prevents Disassembly of Cell Junctions and Activities of MMPs in Invasive Human Pancreas Cancer Cells through ERK/NF- kappa B/Snail Signal Transduction Pathway.	gingerol	0-12	mitogen-activated protein kinase 1	Homo sapiens	123-126	
24204396-5	2013	Furthermore, NF- kappa B/Snail nuclear translocation was suppressed via downregulation of the extracellular signal-regulated kinase (ERK) pathway in response to [6]-gingerol treatment.	gingerol	165-173	mitogen-activated protein kinase 1	Homo sapiens	94-131	
24204396-5	2013	Furthermore, NF- kappa B/Snail nuclear translocation was suppressed via downregulation of the extracellular signal-regulated kinase (ERK) pathway in response to [6]-gingerol treatment.	gingerol	165-173	mitogen-activated protein kinase 1	Homo sapiens	133-136	
24204396-7	2013	In conclusion, these findings demonstrate that [6]-gingerol regulates TJ-related proteins and suppresses invasion and metastasis through NF- kappa B/Snail inhibition via inhibition of the ERK pathway.	gingerol	47-59	mitogen-activated protein kinase 1	Homo sapiens	188-191	
19671252-7	2009	Suppression of IL-1 beta-induced MUC5AC mRNA was also observed in cells pretreated with ERK- or p38 MAPK-specific inhibitors, suggesting that [6]-gingerol-mediated suppression of IL-1 beta-induced MUC5AC mRNA operated via the ERK- and p38 MAPK-dependent pathways.	gingerol	146-154	mitogen-activated protein kinase 1	Homo sapiens	88-91	
19671252-7	2009	Suppression of IL-1 beta-induced MUC5AC mRNA was also observed in cells pretreated with ERK- or p38 MAPK-specific inhibitors, suggesting that [6]-gingerol-mediated suppression of IL-1 beta-induced MUC5AC mRNA operated via the ERK- and p38 MAPK-dependent pathways.	gingerol	146-154	mitogen-activated protein kinase 1	Homo sapiens	226-229	
19671252-8	2009	CONCLUSIONS: [6]-Gingerol suppresses IL-1 beta -induced MUC5AC gene expression in human airway epithelial cells via the ERK- and p38 MAPK-dependent pathways; therefore, [6]-gingerol may be considered a possible anti-hypersecretory agent.	gingerol	17-25	mitogen-activated protein kinase 1	Homo sapiens	120-123