PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22719783-7 2012 Our findings revealed that levels of cyclin A, cyclin B1, and CDK1 were diminished; in contrast, levels of the negative cell cycle regulators p27(Kip1) and p21(Cip1) were increased in response to 6-gingerol treatment. gingerol 196-206 cyclin dependent kinase inhibitor 1A Homo sapiens 156-159 22719783-9 2012 These findings indicate that exposure of 6-gingerol may induce intracellular ROS and upregulate p53, p27(Kip1), and p21(Cip1) levels leading to consequent decrease of CDK1, cyclin A, and cyclin B1 as result of cell cycle arrest in LoVo cells. gingerol 41-51 cyclin dependent kinase inhibitor 1A Homo sapiens 116-119 22719783-9 2012 These findings indicate that exposure of 6-gingerol may induce intracellular ROS and upregulate p53, p27(Kip1), and p21(Cip1) levels leading to consequent decrease of CDK1, cyclin A, and cyclin B1 as result of cell cycle arrest in LoVo cells. gingerol 41-51 cyclin dependent kinase inhibitor 1A Homo sapiens 120-124 22719783-7 2012 Our findings revealed that levels of cyclin A, cyclin B1, and CDK1 were diminished; in contrast, levels of the negative cell cycle regulators p27(Kip1) and p21(Cip1) were increased in response to 6-gingerol treatment. gingerol 196-206 cyclin dependent kinase inhibitor 1A Homo sapiens 160-164