PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26939769-5	2016	This gingerol-induced increase of IFN-gamma secretion could be blocked by the specific TRPV1 antagonist SB-366791.	gingerol	5-13	transient receptor potential cation channel subfamily V member 1	Homo sapiens	87-92	
27606946-6	2016	In addition, in silico docking simulation and a subsequent mutational study suggested that [6]-gingerol might bind to and activate TRPV1 in a unique manner.	gingerol	91-103	transient receptor potential cation channel subfamily V member 1	Homo sapiens	131-136	
26939769-6	2016	The results of the present study point to an interaction of gingerols with TRPV1 in activated T lymphocytes leading to an augmentation of IFN-gamma secretion.	gingerol	60-69	transient receptor potential cation channel subfamily V member 1	Homo sapiens	75-80	
23956783-9	2013	We found that S-[6]-gingerol induced rapid NF kappa B activation through TRPV1 in HuH-7 cells.	gingerol	14-28	transient receptor potential cation channel subfamily V member 1	Homo sapiens	73-78	
23956783-10	2013	Furthermore, S-[6]-gingerol-induced NF kappa B activation was dependent on the calcium gradient and TRPV1.	gingerol	13-27	transient receptor potential cation channel subfamily V member 1	Homo sapiens	100-105	
22257892-0	2012	Synthesis and biological evaluation of [6]-gingerol analogues as transient receptor potential channel TRPV1 and TRPA1 modulators.	gingerol	43-51	transient receptor potential cation channel subfamily V member 1	Homo sapiens	102-107	
22257892-2	2012	The exploration of the structure-activity relationships, by modulating the three pharmacophoric regions of [6]-gingerol, led to the identification of some selective TRPV1 agonists/desensitizers of TRPV1 channels (3a, 3f, and 4) and of some full TRPA1 antagonists (2c, 2d, 3b, and 3d).	gingerol	107-119	transient receptor potential cation channel subfamily V member 1	Homo sapiens	165-170	
22257892-2	2012	The exploration of the structure-activity relationships, by modulating the three pharmacophoric regions of [6]-gingerol, led to the identification of some selective TRPV1 agonists/desensitizers of TRPV1 channels (3a, 3f, and 4) and of some full TRPA1 antagonists (2c, 2d, 3b, and 3d).	gingerol	107-119	transient receptor potential cation channel subfamily V member 1	Homo sapiens	197-202	
14599363-6	2002	However, a subset of agonists (tinyatoxin, gingerol, and zingerone) was approximately 10-fold more potent for rVR1 compared to hVR1.	gingerol	43-51	transient receptor potential cation channel subfamily V member 1	Homo sapiens	127-131	
23956783-4	2013	Previously, we reported that S-[6]-gingerol is an efficacious agonist of the transient receptor potential cation channel subfamily V member 1 (TRPV1) in neurones.	gingerol	29-43	transient receptor potential cation channel subfamily V member 1	Homo sapiens	77-141	
23956783-4	2013	Previously, we reported that S-[6]-gingerol is an efficacious agonist of the transient receptor potential cation channel subfamily V member 1 (TRPV1) in neurones.	gingerol	29-43	transient receptor potential cation channel subfamily V member 1	Homo sapiens	143-148	
23956783-7	2013	The increase in [Ca(2+)] i induced by S-[6]-gingerol was abolished by preincubation with EGTA and was also inhibited by the TRPV1 channel antagonist capsazepine.	gingerol	38-52	transient receptor potential cation channel subfamily V member 1	Homo sapiens	124-129	
17176640-3	2006	All the gingerols and shogaols increased intracellular calcium concentration in rat transient receptor potential vanilloid subtype 1 (TRPV1)-expressing HEK293 cells via TRPV1.	gingerol	8-17	transient receptor potential cation channel subfamily V member 1	Homo sapiens	169-174