PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30187878-0	2018	[10-gingerol inhibits proliferation of hepatocellular carcinoma HepG2 cells via Src/STAT3 signaling pathway].	gingerol	1-12	signal transducer and activator of transcription 3	Homo sapiens	84-89	
30187878-8	2018	Western blotting showed that 10-gingerol at 3 and 10 mumol/L significantly decreased the phosphorylation levels of Src and STAT3 in HepG2 cells (P < 0.01).	gingerol	29-40	signal transducer and activator of transcription 3	Homo sapiens	123-128	
30187878-10	2018	CONCLUSIONS: 10-gingerol can dose-dependently inhibit the proliferation of HepG2 cells and suppress the activation of Src and STAT3.	gingerol	13-24	signal transducer and activator of transcription 3	Homo sapiens	126-131	
22714996-5	2012	6-Gingerol and 6-shogaol concentrations of >= 10 muM and >= 2.5 muM, respectively, significantly inhibited the phosphorylation of mitogen-activated protein kinase (MAPK) and PI3K/Akt signaling, the activation of NF-kappaB, and the translocation of NF-kappaB and STAT3.	gingerol	0-10	signal transducer and activator of transcription 3	Homo sapiens	268-273	
24962868-7	2015	Compared with other analogues of 6SG, such as 6-gingerol (6G), 8-gingerol (8G), and 10-gingerol (10G), 6SG was found to be the most potent blocker of STAT3 activation.	gingerol	84-95	signal transducer and activator of transcription 3	Homo sapiens	150-155	
22714996-7	2012	CONCLUSION: 6-Shogaol and 6-gingerol effectively inhibit invasion and metastasis of hepatocellular carcinoma through diverse molecular mechanisms, including inhibition of the MAPK and PI3k/Akt pathways and NF-kappaB and STAT3 activities to suppress expression of MMP-2/-9 and uPA and block angiogenesis.	gingerol	26-36	signal transducer and activator of transcription 3	Homo sapiens	220-225	
32681941-0	2020	6-Gingerol attenuates microglia-mediated neuroinflammation and ischemic brain injuries through Akt-mTOR-STAT3 signaling pathway.	gingerol	0-10	signal transducer and activator of transcription 3	Homo sapiens	104-109	
33496116-9	2020	The results of molecular docking showed that baicalein,berberine,licochalcone A and 6-gingerol had a high affinity with SRC,STAT3,TNF and IL6.	gingerol	84-94	signal transducer and activator of transcription 3	Homo sapiens	124-129	
32681941-8	2020	In terms of mechanism, 6-Gingerol potently suppressed phosphorylation of serine-threonine protein kinase (Akt) - mammalian target of rapamycin (mTOR) - signal transducer and activator of transcription 3 (STAT3) in LPS-treated microglia.	gingerol	23-33	signal transducer and activator of transcription 3	Homo sapiens	152-202	
32681941-8	2020	In terms of mechanism, 6-Gingerol potently suppressed phosphorylation of serine-threonine protein kinase (Akt) - mammalian target of rapamycin (mTOR) - signal transducer and activator of transcription 3 (STAT3) in LPS-treated microglia.	gingerol	23-33	signal transducer and activator of transcription 3	Homo sapiens	204-209	
32681941-9	2020	Taken together, the present study suggested that 6-Gingerol improved cerebral ischemia injury by suppressing microglia-mediated neuroinflammation by down-regulating Akt-mTOR-STAT3 pathway.	gingerol	49-59	signal transducer and activator of transcription 3	Homo sapiens	174-179	
30942163-0	2019	6-Gingerol inhibits proliferation in gastric cancer via the STAT3 pathway in vitro.	gingerol	0-10	signal transducer and activator of transcription 3	Homo sapiens	60-65	
30963995-0	2019	Retraction: 6-Gingerol inhibits proliferation in gastric cancer via the STAT3 pathway in vitro.	gingerol	12-22	signal transducer and activator of transcription 3	Homo sapiens	72-77