PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32681941-0	2020	6-Gingerol attenuates microglia-mediated neuroinflammation and ischemic brain injuries through Akt-mTOR-STAT3 signaling pathway.	gingerol	0-10	mechanistic target of rapamycin kinase	Homo sapiens	99-103	
34697150-0	2021	(6)-Gingerol Suppresses Oral Cancer Cell Growth by Inducing the Activation of AMPK and Suppressing the AKT/mTOR Signaling Pathway.	gingerol	0-12	mechanistic target of rapamycin kinase	Homo sapiens	107-111	
34697150-8	2021	Moreover, (6)-gingerol induced the activation of AMPK and suppressed the AKT/mTOR signaling pathway in YD10B and Ca9-22 cells.	gingerol	10-22	mechanistic target of rapamycin kinase	Homo sapiens	77-81	
34697150-9	2021	CONCLUSION: (6)-Gingerol exerts anticancer activity by activating AMPK and suppressing the AKT/mTOR signaling pathway in oral cancer cells.	gingerol	12-24	mechanistic target of rapamycin kinase	Homo sapiens	95-99	
32681941-8	2020	In terms of mechanism, 6-Gingerol potently suppressed phosphorylation of serine-threonine protein kinase (Akt) - mammalian target of rapamycin (mTOR) - signal transducer and activator of transcription 3 (STAT3) in LPS-treated microglia.	gingerol	23-33	mechanistic target of rapamycin kinase	Homo sapiens	113-142	
32681941-8	2020	In terms of mechanism, 6-Gingerol potently suppressed phosphorylation of serine-threonine protein kinase (Akt) - mammalian target of rapamycin (mTOR) - signal transducer and activator of transcription 3 (STAT3) in LPS-treated microglia.	gingerol	23-33	mechanistic target of rapamycin kinase	Homo sapiens	144-148	
32681941-9	2020	Taken together, the present study suggested that 6-Gingerol improved cerebral ischemia injury by suppressing microglia-mediated neuroinflammation by down-regulating Akt-mTOR-STAT3 pathway.	gingerol	49-59	mechanistic target of rapamycin kinase	Homo sapiens	169-173	
28249781-5	2017	6-Gingerol activated AMPK, but inhibited PI3K/AKT phosphorylation with reduced P70S6K expression and also suppressed the mTOR phosphorylation.	gingerol	0-10	mechanistic target of rapamycin kinase	Homo sapiens	121-125	
27451028-8	2016	It has been demonstrated that 6-gingerol suppressed the phosphatidylinositol 3-kinase (PI3K)/AKT/mTOR signaling pathway, increased the expression of Beclin1 to promote autophagy, and increased Bcl-2 expression to inhibit apoptosis.	gingerol	30-40	mechanistic target of rapamycin kinase	Homo sapiens	97-101