PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32438504-0	2020	[6]-Gingerol Ameliorates ISO-induced Myocardial Fibrosis by Reducing Oxidative Stress, Inflammation and Apoptosis Through Inhibition of TLR4/MAPKs/NF-kappaB Pathway.	gingerol	0-12	toll-like receptor 4	Mus musculus	136-140	
17291534-5	2007	We hypothesized that the anti-inflammatory effect of 6-gingerol is because of inhibition of macrophage activation, more specifically by an inhibition of pro-inflammatory cytokines and antigen presentation by lipopolysaccharide (LPS) activated macrophages.	gingerol	53-63	toll-like receptor 4	Mus musculus	228-231	
17291534-9	2007	RESULTS: 6-gingerol inhibited the production of pro-inflammatory cytokines from LPS stimulated macrophages but had no effect on the LPS-induced expression of B7.1, B7.2, and MHC II.	gingerol	9-19	toll-like receptor 4	Mus musculus	80-83	
32438504-9	2020	Further, [6]-gingerol improved ISO-induced morphological pathologies, reduced the expression of TNF-alpha, IL-6, c-fos, c-jun, Bax, Caspase-3, TLR4, NF-kappaB, p38, p-p38, ERK1/2, p-ERK1/2, JNK, and p-JNK, and increased Bcl-2 protein expression.	gingerol	9-21	toll-like receptor 4	Mus musculus	143-147	
32438504-10	2020	CONCLUSION: The protective effect of [6]-gingerol in mice with ISO-induced myocardial fibrosis may be related to the inhibition of oxidative stress, inflammation, and apoptosis, potentially through the TLR4/MAPKs/NF-kappaB signaling pathway.	gingerol	37-49	toll-like receptor 4	Mus musculus	202-206