PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8595642-6 1995 Lovastatin significantly decreased levels of total cholesterol, calculated LDL, directly measured LDL, IDL, total triglycerides, VLDL, and the ratios of LDL:HDL, total cholesterol:HDL, and directly measured LDL:HDL and significantly increased total HDL and HDL3 levels. Lovastatin 0-10 HDL3 Homo sapiens 257-261 8595642-7 1995 Gemfibrozil was significantly more effective than lovastatin in raising total HDL and HDL3 levels and in lowering the IDL plus VLDL:HDL ratio. Lovastatin 50-60 HDL3 Homo sapiens 86-90 1613316-3 1992 Gemfibrozil and lovastatin caused primarily similar alterations in HDL components in HDL2 and HDL3 subfractions. Lovastatin 16-26 HDL3 Homo sapiens 94-98 8434806-2 1993 Lovastatin therapy caused greater percentage changes in HDL2 than in HDL3. Lovastatin 0-10 HDL3 Homo sapiens 69-73 1613316-6 1992 Gemfibrozil increased the cholesterol concentrations of HDL2 and HDL3 (p less than 0.05 for both), and lovastatin caused significant increases in HDL2 (p less than 0.05) and HDL3 phospholipids (p less than 0.01). Lovastatin 103-113 HDL3 Homo sapiens 174-178 2079605-3 1990 Lovastatin caused reduction of the apparent number of 125I-labeled HDL3 binding sites without affecting the binding affinity. Lovastatin 0-10 HDL3 Homo sapiens 67-71 2079605-5 1990 Mevalonic acid reversed the effect of lovastatin on 125I-labeled HDL3 binding. Lovastatin 38-48 HDL3 Homo sapiens 65-69 2079605-6 1990 Lovastatin blocked up-regulation of the HDL receptor in response to loading of cells with nonlipoprotein cholesterol and modified cholesterol-induced changes of 125I-labeled HDL3 degradation. Lovastatin 0-10 HDL3 Homo sapiens 174-178