PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12526087-4 2002 In this study we investigated the expression of intercellular cell adhesion molecule-1 (ICAM-1) in transformed endothelial cell line ECV304 cells as influenced by lovastatin, tumor necrosis factor-alpha (TNF-alpha) and IFN-gamma. Lovastatin 163-173 intercellular adhesion molecule 1 Homo sapiens 48-86 15955822-9 2005 When LFA-1 was shifted into the low affinity state by lovastatin, both monomeric and dimeric ICAM-1 dissociated in less than 1 s, and the dissociation rates were within 50% of each other. Lovastatin 54-64 intercellular adhesion molecule 1 Homo sapiens 93-99 12526087-6 2002 In cells treated with lovastatin and IFN-gamma, ICAM-1 was expressed at a lower level than in cells treated with IFN-gamma alone. Lovastatin 22-32 intercellular adhesion molecule 1 Homo sapiens 48-54 12526087-4 2002 In this study we investigated the expression of intercellular cell adhesion molecule-1 (ICAM-1) in transformed endothelial cell line ECV304 cells as influenced by lovastatin, tumor necrosis factor-alpha (TNF-alpha) and IFN-gamma. Lovastatin 163-173 intercellular adhesion molecule 1 Homo sapiens 88-94 12526087-5 2002 Results show that lovastatin suppresses expression of ICAM-1 by inhibiting the IFN-gamma-induced extracellular signal-regulated kinase (ERK) p44/p42-STAT1 signaling pathway. Lovastatin 18-28 intercellular adhesion molecule 1 Homo sapiens 54-60 12119193-0 2002 Lovastatin-stimulated superinduction of E-selectin, ICAM-1 and VCAM-1 in TNF-alpha activated human vascular endothelial cells. Lovastatin 0-10 intercellular adhesion molecule 1 Homo sapiens 52-58 26517522-3 2016 Lovastatin inhibited the expressions of transforming growth factor (TGF)-beta1, cyclooxygenase (COX)-2, and intercellular adhesion molecule (ICAM)-1. Lovastatin 0-10 intercellular adhesion molecule 1 Homo sapiens 108-148 11226249-5 2001 Lovastatin, which binds under the conformationally mobile C-terminal alpha-helix of the I domain, inhibited binding to ICAM-1 by alphaLbeta2 with wild-type, but not locked-open I domains. Lovastatin 0-10 intercellular adhesion molecule 1 Homo sapiens 119-125 26517522-5 2016 While Lovastatin"s inhibitory effects on TGFbeta1, COX2, and ICAM-1 expression were independently controlled by the tumor suppressor LKB1, integrin beta3 expression was not affected. Lovastatin 6-16 intercellular adhesion molecule 1 Homo sapiens 61-67 19254713-12 2009 Towards the mechanism, we showed that lovastatin ameliorated ICAM-1 expression-induced by hypoxia and TNF-alpha in both RCECs and ARPE-19 cells, in part through inhibition of NF-kappaB activation. Lovastatin 38-48 intercellular adhesion molecule 1 Homo sapiens 61-67 25374755-12 2014 Activated BEAS-2B cells treated with lovastatin exhibited reduced IL-6, eotaxins (CCL11 and CCL24), and intercellular adhesion molecule-1 protein expression. Lovastatin 37-47 intercellular adhesion molecule 1 Homo sapiens 104-137