PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26309556-7	2015	The 6-OHDA-stimulated mRNA and protein levels of TNF-alpha IL-6 and IL-1beta were reduced by lovastatin.	Lovastatin	93-103	tumor necrosis factor	Rattus norvegicus	49-58	
28061433-7	2017	Lovastatin inhibited oxidative stress induced by multiple oxidants including ox-LDL, H2O2, TNFalpha, homocysteine thiolactone (HTL), and high glucose (HG), which were reversed by inhibition of miR-29b in HUVECs.	Lovastatin	0-10	tumor necrosis factor	Rattus norvegicus	91-99	
25419363-5	2014	Our results show that lovastatin significantly decreased both the mRNA and the protein levels of TNF-alpha and NMDAR1.	Lovastatin	22-32	tumor necrosis factor	Rattus norvegicus	97-106	
25419363-7	2014	Our results suggest that lovastatin induces neuroprotection by inhibiting NMDAR1 and TNF-alpha.	Lovastatin	25-35	tumor necrosis factor	Rattus norvegicus	85-94	
10430507-8	1999	Administration of lovastatin inhibited the expression of iNOS, TNF-alpha and IFN-gamma in the CNS of EAE rats and improved the clinical signs of EAE suggesting that this compound may have therapeutic potential in the treatment of neuroinflammatory diseases like MS.	Lovastatin	18-28	tumor necrosis factor	Rattus norvegicus	63-72	
21130693-4	2011	Quantitative real-time polymerase chain reaction showed a significant decrease in mRNA expression of interleukin-1beta, interleukin-6, tumor necrosis factor alpha, and kinin B1 receptor in animals with SE treated with lovastatin, compared with untreated animals with SE (P<0.001).	Lovastatin	218-228	tumor necrosis factor	Rattus norvegicus	135-162	
17612572-12	2007	Our results show that pre-administration of lovastatin improved functional outcomes and reduced extent of brain damage, with a concomitant decrease in tissue levels of TNF-alpha and IL-1beta mRNA and protein.	Lovastatin	44-54	tumor necrosis factor	Rattus norvegicus	168-177	
17126835-10	2007	Lovastatin also reduced the accumulation of microglia and decreased the expression of TNF-alpha in the demyelinative lesions.	Lovastatin	0-10	tumor necrosis factor	Rattus norvegicus	86-95	
24857811-9	2014	The pilocarpine plus lovastatin group showed a significant decrease in the levels of IL-1beta, TNF-alpha, and IL-6 during the latent phase and a decreased expression of IL-1beta and TNF-alpha in the chronic phase when compared with the PILO group.	Lovastatin	21-31	tumor necrosis factor	Rattus norvegicus	95-104	
24857811-9	2014	The pilocarpine plus lovastatin group showed a significant decrease in the levels of IL-1beta, TNF-alpha, and IL-6 during the latent phase and a decreased expression of IL-1beta and TNF-alpha in the chronic phase when compared with the PILO group.	Lovastatin	21-31	tumor necrosis factor	Rattus norvegicus	182-191	
9389730-6	1997	In addition to iNOS, lovastatin and NaPA also inhibited LPS-induced expression of TNF-alpha, IL-1beta, and IL-6 in rat primary astrocytes, microglia, and macrophages.	Lovastatin	21-31	tumor necrosis factor	Rattus norvegicus	82-91