PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7684605-8	1993	Administration of 10 mg/day lovastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, markedly attenuated both the reduced basal NO production and the increased adhesiveness of the endothelium.	Lovastatin	28-38	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oryctolagus cuniculus	42-89	
10794499-4	2000	The action of L-arginine was compared to vitamin E and the HMG CoA reductase inhibitor lovastatin which are known to attenuate progression of atherosclerosis.	Lovastatin	87-97	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oryctolagus cuniculus	59-76	
9247534-1	1997	OBJECTIVES: We sought to document the common mechanisms of the antiatherogenic effects of the cholesterol-lowering hydroxy-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor lovastatin, the dihydropyridine Ca2+ blocker amlodipine and the antioxidant vitamin E.	Lovastatin	179-189	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oryctolagus cuniculus	115-168	
3076120-3	1988	Treatment of these animals with the HMG CoA reductase inhibitor lovastatin from the time of weaning results in a significant degree of inhibition of lesion formation.	Lovastatin	64-74	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oryctolagus cuniculus	36-53	
8516264-1	1993	The aim of the present study was to investigate the effect of the hydroxymethylglutaryl (HMG)-CoA reductase inhibitor lovastatin on some aspects of cholesterol metabolism in cholesterol-fed rabbits.	Lovastatin	118-128	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oryctolagus cuniculus	66-107	
2776246-1	1989	Relatively high concentrations of MK-733 (simvastatin) and MK-803 (lovastatin, mevinolin), which are 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, were found to inhibit acyl coenzyme A: cholesterol acyltransferase (ACAT) of rabbit intestinal microsomes with IC50"s of 2.0 x 10(-5) and 3.6 x 10(-5) M, respectively.	Lovastatin	59-65	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oryctolagus cuniculus	101-158	
2776246-1	1989	Relatively high concentrations of MK-733 (simvastatin) and MK-803 (lovastatin, mevinolin), which are 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, were found to inhibit acyl coenzyme A: cholesterol acyltransferase (ACAT) of rabbit intestinal microsomes with IC50"s of 2.0 x 10(-5) and 3.6 x 10(-5) M, respectively.	Lovastatin	67-77	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oryctolagus cuniculus	101-158	
2776246-1	1989	Relatively high concentrations of MK-733 (simvastatin) and MK-803 (lovastatin, mevinolin), which are 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, were found to inhibit acyl coenzyme A: cholesterol acyltransferase (ACAT) of rabbit intestinal microsomes with IC50"s of 2.0 x 10(-5) and 3.6 x 10(-5) M, respectively.	Lovastatin	79-88	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oryctolagus cuniculus	101-158	
2918466-6	1989	All histopathological and serum biochemical changes induced by lovastatin were completely prevented by coadministration of mevalonate, the product of the inhibited HMG-CoA reductase enzyme.	Lovastatin	63-73	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oryctolagus cuniculus	164-181