PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15380892-8 2004 CONCLUSION: It would appear that both naringin and lovastatin contributed to hypocholesterolemic action via down-regulated ACAT activity and higher excretion of fecal sterols in response to high-cholesterol feeding. Lovastatin 51-61 sterol O-acyltransferase 1 Oryctolagus cuniculus 123-127 2776246-1 1989 Relatively high concentrations of MK-733 (simvastatin) and MK-803 (lovastatin, mevinolin), which are 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, were found to inhibit acyl coenzyme A: cholesterol acyltransferase (ACAT) of rabbit intestinal microsomes with IC50"s of 2.0 x 10(-5) and 3.6 x 10(-5) M, respectively. Lovastatin 59-65 sterol O-acyltransferase 1 Oryctolagus cuniculus 239-243 2776246-1 1989 Relatively high concentrations of MK-733 (simvastatin) and MK-803 (lovastatin, mevinolin), which are 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, were found to inhibit acyl coenzyme A: cholesterol acyltransferase (ACAT) of rabbit intestinal microsomes with IC50"s of 2.0 x 10(-5) and 3.6 x 10(-5) M, respectively. Lovastatin 67-77 sterol O-acyltransferase 1 Oryctolagus cuniculus 239-243 2776246-1 1989 Relatively high concentrations of MK-733 (simvastatin) and MK-803 (lovastatin, mevinolin), which are 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, were found to inhibit acyl coenzyme A: cholesterol acyltransferase (ACAT) of rabbit intestinal microsomes with IC50"s of 2.0 x 10(-5) and 3.6 x 10(-5) M, respectively. Lovastatin 79-88 sterol O-acyltransferase 1 Oryctolagus cuniculus 239-243