PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31079432-11	2019	Results: Simultaneous or sequential treatment of TGF-beta1 and lovastatin could further augment the BMP-2 overexpression compared with lovastatin-alone treatment.	Lovastatin	63-73	bone morphogenetic protein 2	Homo sapiens	100-105	
12593849-0	2003	Lovastatin stimulates human vascular smooth muscle cell expression of bone morphogenetic protein-2, a potent inhibitor of low-density lipoprotein-stimulated cell growth.	Lovastatin	0-10	bone morphogenetic protein 2	Homo sapiens	70-98	
12593849-3	2003	Treatment with the 3-hydroxy-3-methylglutaryl coenzyme A inhibitor lovastatin (34 microM) increased BMP-2 gene transcription >14-fold as measured by real-time PCR analysis (P<0.05 vs. solvent control).	Lovastatin	67-77	bone morphogenetic protein 2	Homo sapiens	100-105	
28367417-0	2017	Lovastatin Reduces Stemness via Epigenetic Reprograming of BMP2 and GATA2 in Human Endometrium and Endometriosis.	Lovastatin	0-10	bone morphogenetic protein 2	Homo sapiens	59-63	
28367417-3	2017	The aim of this study was to investigate whether lovastatin treatment could influence expression and methylation patterns of genes regulating differentiation of endometrial mesenchymal stem cells (eMSCs) such as BMP2, GATA2 and RUNX2 as well as eMSCs markers.	Lovastatin	49-59	bone morphogenetic protein 2	Homo sapiens	212-216	
28367417-7	2017	RESULTS: In the present study, treatment with lovastatin increased expression of BMP2 and RUNX2 and induced BMP2 promoter demethylation.	Lovastatin	46-56	bone morphogenetic protein 2	Homo sapiens	81-85	
28367417-7	2017	RESULTS: In the present study, treatment with lovastatin increased expression of BMP2 and RUNX2 and induced BMP2 promoter demethylation.	Lovastatin	46-56	bone morphogenetic protein 2	Homo sapiens	108-112	
25846724-11	2015	Prolonged exposure to high concentrations of lovastatin induced changes in cytoskeleton leading to cell rounding and decreased levels of mRNA for matrix proteins, but increased BMP-2 expression.	Lovastatin	45-55	bone morphogenetic protein 2	Homo sapiens	177-182	
17179158-1	2007	Lovastatin promotes osteoblast differentiation by increasing bone morphogenetic protein-2 (BMP-2) expression.	Lovastatin	0-10	bone morphogenetic protein 2	Homo sapiens	61-89	
19602044-6	2009	Simvastatin and lovastatin enhanced bone morphogenetic protein 2 (BMP-2) mRNA levels.	Lovastatin	16-26	bone morphogenetic protein 2	Homo sapiens	36-64	
19602044-6	2009	Simvastatin and lovastatin enhanced bone morphogenetic protein 2 (BMP-2) mRNA levels.	Lovastatin	16-26	bone morphogenetic protein 2	Homo sapiens	66-71	
20883448-5	2011	At lovastatin concentrations >=1 microM, expression of genes encoding the bone morphogenetic proteins BMP-2 and BMP-7 was also significantly enhanced.	Lovastatin	3-13	bone morphogenetic protein 2	Homo sapiens	105-110	
17179158-1	2007	Lovastatin promotes osteoblast differentiation by increasing bone morphogenetic protein-2 (BMP-2) expression.	Lovastatin	0-10	bone morphogenetic protein 2	Homo sapiens	91-96	
17179158-4	2007	Expression of dominant-negative PI3K and PTEN, an inhibitor of PI3K signaling, significantly attenuated lovastatin-induced transcription of BMP-2.	Lovastatin	104-114	bone morphogenetic protein 2	Homo sapiens	140-145	
17179158-7	2007	Lovastatin-induced Erk1/2 activity contributed to BMP-2 transcription.	Lovastatin	0-10	bone morphogenetic protein 2	Homo sapiens	50-55	
17179158-9	2007	We provide, as a mechanism of this cross-talk, the first evidence that lovastatin stimulates rapid activation of Ras, which associates with and activates PI3K in the plasma membrane, which in turn regulates Akt and Erk1/2 to induce BMP-2 expression for osteoblast differentiation.	Lovastatin	71-81	bone morphogenetic protein 2	Homo sapiens	232-237