PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35571660-11	2022	The principal finding of this research was that lovastatin still suppressed A549 cell growth after LPS+ATP stimulation via modulation of ERK1/2, c-JUN, COX-2, BCL-2, and BAX protein levels (P<0.05).	Lovastatin	48-58	BCL2 associated X, apoptosis regulator	Homo sapiens	170-173	
26409448-9	2016	Similar to the RhoA siRNA transfectants, lovastatin treatment downregulated RhoA, MMP2, MMP9, and cyclinA1 protein expression, while upregulating that of Bax as compared to that of the NC (p &lt; 0.05).	Lovastatin	41-51	BCL2 associated X, apoptosis regulator	Homo sapiens	154-157	
18034278-8	2008	Lovastatin induces apoptosis and necrosis in lung cancer cell lines by causing alterations in the cell cycle, reducing glutathione, and activating p53, Bax protein, and caspases while increasing cytochrome c in apoptosis pathways.	Lovastatin	0-10	BCL2 associated X, apoptosis regulator	Homo sapiens	152-155	
23764197-7	2013	Lovastatin exposure induced lower RhoC, bcl-2, matrix metalloproteinase-9 (MMP-9), survivin, Akt, bcl-xL, vascular endothelial growth factor (VEGF), and p-p70s6k expression in OVCAR3 compared to the control, but higher caspase-3 and Bax expression.	Lovastatin	0-10	BCL2 associated X, apoptosis regulator	Homo sapiens	233-236	
12094262-5	2002	This effect was not the consequence of a change in the protein expression levels of Bcl-2 or Bax induced by lovastatin.	Lovastatin	108-118	BCL2 associated X, apoptosis regulator	Homo sapiens	93-96	
16523333-14	2006	In most patients, the BCL-2/BAX ratio was lower in cell cultures supplemented with mixture of lovastatin and thalidomide in comparison with cell cultures supplemented with lovastatin or thalidomide alone.	Lovastatin	94-104	BCL2 associated X, apoptosis regulator	Homo sapiens	28-31	
10473109-6	1999	Lovastatin treatment resulted in decreased expression of the antiapoptotic protein bcl-2 and increased the expression of the proapoptotic protein bax.	Lovastatin	0-10	BCL2 associated X, apoptosis regulator	Homo sapiens	146-149