PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10205288-10 1999 The data demonstrate that lovastatin can suppress PDGF- and angiotensin II-mediated induction of c-Jun and c-Fos protein in human SMC. Lovastatin 26-36 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 107-112 2115642-4 1990 Our results show that pretreatment of quiescent human fibroblasts with mevinolin, an HMG CoA reductase inhibitor, partially suppresses fos and myc mRNA accumulation in response to serum stimulation. Lovastatin 71-80 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 135-138 9430371-3 1997 The present study addressed the question whether the inhibitory effect of lovastatin on premitotic DNA synthesis correlates with a downregulation of c-fos mRNA levels, a marker of signaling efficiency, in human SMC. Lovastatin 74-84 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 149-154 9430371-6 1997 Lovastatin efficiently inhibited [3H]thymidine uptake promoted by all mitogens tested (76-87%); however, it significantly inhibited upregulation of c-fos mRNA levels induced only by insulin (33-67%, P < 0.05) and IGF-I (31 57%, P < 0.05). Lovastatin 0-10 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 148-153