PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34911669-7 2022 Importantly, domain I of nsp4 inhibited Sendai virus-induced interferon beta production, and this inhibitory effect was eliminated by Lovastatin, an HMGCR inhibitor, indicating that the upregulation of cellular cholesterol by nsp4 is a strategy used by PRRSV to suppress the antiviral innate immunity of its host. Lovastatin 134-144 interferon beta 1 Homo sapiens 61-76 20526818-8 2010 IFN-beta causes up-regulated and lovastatin down-regulated expression of CD86, which results in a biased Th-cell responses in MS. Lovastatin 33-43 interferon beta 1 Homo sapiens 0-8