PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16741367-1 2006 BACKGROUND: Desloratadine is an H1-histamine antagonist which possesses additional anti-inflammatory properties through inhibition of leukocyte activation and reduction of ICAM-1 expression on mucosal epithelial cells. desloratadine 12-25 intercellular adhesion molecule 1 Homo sapiens 172-178 7677235-0 1995 Inhibitory activity of loratadine and descarboethoxyloratadine on expression of ICAM-1 and HLA-DR by nasal epithelial cells. desloratadine 38-62 intercellular adhesion molecule 1 Homo sapiens 80-86 11496238-0 2001 Effect of desloratadine and loratadine on rhinovirus-induced intercellular adhesion molecule 1 upregulation and promoter activation in respiratory epithelial cells. desloratadine 10-23 intercellular adhesion molecule 1 Homo sapiens 61-94 11496238-6 2001 OBJECTIVE: We have investigated the effects of desloratadine and loratadine on rhinovirus-induced ICAM-1 expression, mRNA upregulation, and promoter activation. desloratadine 47-60 intercellular adhesion molecule 1 Homo sapiens 98-104 11496238-10 2001 RESULTS: Desloratadine and loratadine (0.1-10 micromol/L) inhibited rhinovirus-induced ICAM-1 upregulation in both primary bronchial or transformed (A549) respiratory epithelial cells. desloratadine 9-22 intercellular adhesion molecule 1 Homo sapiens 87-93 11496238-12 2001 Desloratadine and loratadine also inhibited ICAM-1 mRNA induction caused by rhinovirus infection in a dose-dependent manner, and they completely inhibited rhinovirus-induced ICAM-1 promoter activation. desloratadine 0-13 intercellular adhesion molecule 1 Homo sapiens 44-50 11496238-12 2001 Desloratadine and loratadine also inhibited ICAM-1 mRNA induction caused by rhinovirus infection in a dose-dependent manner, and they completely inhibited rhinovirus-induced ICAM-1 promoter activation. desloratadine 0-13 intercellular adhesion molecule 1 Homo sapiens 174-180