PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16530440-1	2007	Anti-inflammatory effect of desloratadine (DL), including, but not limited to depression of production of IL-4, IL-6 and IL-8, has been shown in several in vitro experiments but only a few in vivo studies refer to this findings.	desloratadine	28-41	interleukin 6	Homo sapiens	112-116	
16530440-1	2007	Anti-inflammatory effect of desloratadine (DL), including, but not limited to depression of production of IL-4, IL-6 and IL-8, has been shown in several in vitro experiments but only a few in vivo studies refer to this findings.	desloratadine	43-45	interleukin 6	Homo sapiens	112-116	
11295678-2	2001	In vitro studies have shown that desloratadine inhibits the release or generation of multiple inflammatory mediators, including IL-4, IL-6, IL-8, IL-13, PGD(2), leukotriene C(4), tryptase, histamine, and the TNF-alpha-induced chemokine RANTES.	desloratadine	33-46	interleukin 6	Homo sapiens	134-138	
32406319-10	2020	The level of interleukin 6 was reduced in desloratadine-treated cells, while upregulation of interleukin 6 significantly abolished the anticancer activity of desloratadine in cell invasion and Bcl-2, Bax, Beclin1, LC3-I/II, N-cadherin, and E-cadherin expression in EJ cells.	desloratadine	42-55	interleukin 6	Homo sapiens	13-26	
32406319-10	2020	The level of interleukin 6 was reduced in desloratadine-treated cells, while upregulation of interleukin 6 significantly abolished the anticancer activity of desloratadine in cell invasion and Bcl-2, Bax, Beclin1, LC3-I/II, N-cadherin, and E-cadherin expression in EJ cells.	desloratadine	158-171	interleukin 6	Homo sapiens	93-106	
32406319-11	2020	Taken together, our data suggest a potential anticancer activity of desloratadine on cell growth and invasion for bladder cancer, which may be mediated by diminishing the epithelial-to-mesenchymal transition and interleukin 6.	desloratadine	68-81	interleukin 6	Homo sapiens	212-225	
21352574-8	2011	In mucosa and polyp epithelial cells, mometasone inhibited this induced secretion while desloratadine inhibited IL-6 and IL-8.	desloratadine	88-101	interleukin 6	Homo sapiens	112-116	
21352574-9	2011	The combination of 10(-5) M desloratadine and 10(-9) M mometasone reduced IL-6 secretion (48 +- 11%, p < 0.05) greater extent than mometasone alone (68 +- 10%) compared to control (100%).	desloratadine	28-41	interleukin 6	Homo sapiens	74-78