PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16393981-0 2006 Sodium salicylate promotes neutrophil apoptosis by stimulating caspase-dependent turnover of Mcl-1. Sodium Salicylate 0-17 caspase 8 Homo sapiens 63-70 16393981-4 2006 Sodium salicylate resulted in rapid activation of caspase-3, -8, -9, and -10, and salicylate-accelerated Mcl-1 turnover was partly blocked by caspase inhibitors. Sodium Salicylate 0-17 caspase 8 Homo sapiens 50-57 16393981-3 2006 Whereas constitutive and GM-CSF-modified Mcl-1 turnover is regulated by the proteasome, the accelerated sodium salicylate-induced Mcl-1 turnover is mediated largely via caspases. Sodium Salicylate 104-121 caspase 8 Homo sapiens 169-177 12041673-0 2002 Sodium salicylate-triggered apoptosis in HL-60 cells depends on caspase-8 activation. Sodium Salicylate 0-17 caspase 8 Homo sapiens 64-73 12041673-8 2002 The findings presented herein strongly suggest that Na-Sal can exert potent killing and proapoptotic activity against HL-60 cells, and this effect appears to depend on caspase-8 activation. Sodium Salicylate 52-58 caspase 8 Homo sapiens 168-177