PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24224485-3 2014 In the present study we show that Rad18 is also capable of enhancing PCNA SUMOylation in a SIM-dependent manner in vitro, most probably by means of directing SUMO-loaded Ubc9 (ubiquitin-conjugating enzyme 9) towards the substrate. ubc9 170-174 E3 ubiquitin-protein ligase RAD18 Saccharomyces cerevisiae S288C 34-39