PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33789427-0 2021 LY3023414 inhibits both osteogenesis and osteoclastogenesis through the PI3K/Akt/GSK3 signalling pathway. LY3023414 0-9 thymoma viral proto-oncogene 1 Mus musculus 77-80 33789427-10 2021 RESULTS: LY3023414 attenuated PI3K/protein kinase B (Akt)/GSK3-dependent activation of beta-catenin and nuclear factor-activated T cell 1 (NFATc1) during osteogenesis and osteoclastogenesis, respectively. LY3023414 9-18 thymoma viral proto-oncogene 1 Mus musculus 53-56 33789427-14 2021 CONCLUSION: LY3023414 can suppress osteogenesis and osteoclastogenesis through inhibition of the PI3K/Akt/GSK3 signalling pathway, which highlights the potential benefits and side effects of LY3023414 for future clinical applications. LY3023414 12-21 thymoma viral proto-oncogene 1 Mus musculus 102-105