PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28623128-8	2017	At the molecular level, LY3023414 blocked PI3K-AKT-mTOR activation in skin SCC cells, as it dephosphorylated PI3K-AKT-mTOR substrates: P85, AKT and S6K1.	LY3023414	24-33	ribosomal protein S6 kinase B1	Homo sapiens	148-152	
27439478-7	2016	In vivo, LY3023414 demonstrated high bioavailability and dose-dependent dephosphorylation of PI3K/AKT/mTOR pathway downstream substrates such as AKT, S6K, S6RP, and 4E-BP1 for 4 to 6 hours, reflecting the drug"s half-life of 2 hours.	LY3023414	9-18	ribosomal protein S6 kinase B1	Homo sapiens	153-159