PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11483530-6 2001 We propose a model in which SMUG1 has evolved in higher eukaryotes as an anti-mutator distinct from the UNG enzyme, the latter being largely localized to replication foci in mammalian cells to counteract de novo dUMP incorporation into DNA. 2'-deoxyuridylic acid 212-216 single-strand-selective monofunctional uracil-DNA glycosylase 1 Homo sapiens 28-33