PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12488542-1 2003 Deoxycytidylate deaminase, catalyzing the conversion of dCMP to dUMP, is an important enzyme in the de novo synthesis of thymidine nucleotides. 2'-deoxyuridylic acid 64-68 dCMP deaminase Homo sapiens 0-25 12771412-2 2003 Here, we have demonstrated that HCMV increases expression of the cellular deoxycytidylate deaminase (dCMP deaminase), which provides the substrate for TS by converting dCMP to dUMP. 2'-deoxyuridylic acid 176-180 dCMP deaminase Homo sapiens 74-99 6581381-8 1983 These data indicate that human neoplastic cell deoxycytidylate deaminase is a highly regulated allosteric enzyme, which is likely to have a significant influence on cellular dUMP, dCTP and TTP pools. 2'-deoxyuridylic acid 174-178 dCMP deaminase Homo sapiens 47-72 31391279-6 2019 We show that overexpression of human dCMP deaminase (DCTD), an enzyme that provides directly dUMP through dCMP deamination, does not reverse the lethal phenotype of dUTPase knockout cells, which further supports the notion that in T. brucei, CDA is uniquely involved in providing dUMP, while the main role of dUTPase would be the withdrawal of the excess of dUTP to avoid its incorporation into DNA. 2'-deoxyuridylic acid 93-97 dCMP deaminase Homo sapiens 53-57 27820863-5 2016 Unlike humans, T. brucei and all other kinetoplastids lack dCMP deaminase (DCTD), which provides an alternative route to dUMP formation. 2'-deoxyuridylic acid 121-125 dCMP deaminase Homo sapiens 75-79