PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29257269-0	2018	Protective effects of psoralidin on IL-1beta-induced chondrocyte apoptosis.	psoralidin	22-32	interleukin 1 beta	Rattus norvegicus	36-44	
29257269-2	2018	The present study aimed to investigate the protective effects of psoralidin on interleukin (IL)-1beta-induced chondrocyte apoptosis and explore the underlying mechanisms.	psoralidin	65-75	interleukin 1 beta	Rattus norvegicus	79-101	
29257269-8	2018	The results of the present study demonstrated that psoralidin may reduce IL-1beta-induced chondrocyte apoptosis.	psoralidin	51-61	interleukin 1 beta	Rattus norvegicus	73-81	
29257269-9	2018	Psoralidin pretreatment also reversed the inhibitory effects of IL-1beta on B-cell lymphoma 2 (Bcl-2) expression, and decreased the IL-1beta-induced expression of Bcl-2-associated X protein, matrix metalloproteinase (MMP)-1 and MMP-13.	psoralidin	0-10	interleukin 1 beta	Rattus norvegicus	64-72	
29257269-9	2018	Psoralidin pretreatment also reversed the inhibitory effects of IL-1beta on B-cell lymphoma 2 (Bcl-2) expression, and decreased the IL-1beta-induced expression of Bcl-2-associated X protein, matrix metalloproteinase (MMP)-1 and MMP-13.	psoralidin	0-10	interleukin 1 beta	Rattus norvegicus	132-140	
29257269-10	2018	Furthermore, psoralidin decreased IL-1beta-induced caspase-3 and -9 activity, NO release, ROS production and nuclear factor (NF)-kappaB nuclear translocation.	psoralidin	13-23	interleukin 1 beta	Rattus norvegicus	34-42	
29257269-11	2018	In addition, the NF-kappaB inhibitor pyrriolidine-dithiocarbamate exerted similar effects to psoralidin, thus suggesting that IL-1beta induced proapoptotic effects in rat chondrocytes via an NF-kappaB-dependent pathway.	psoralidin	93-103	interleukin 1 beta	Rattus norvegicus	126-134	
29257269-12	2018	Since psoralidin could protect chondrocytes from IL-1beta-induced apoptosis and MMP expression, the present results suggested that psoralidin may be considered a drug candidate for the treatment of osteoarthritis.	psoralidin	6-16	interleukin 1 beta	Rattus norvegicus	49-57	
29257269-12	2018	Since psoralidin could protect chondrocytes from IL-1beta-induced apoptosis and MMP expression, the present results suggested that psoralidin may be considered a drug candidate for the treatment of osteoarthritis.	psoralidin	131-141	interleukin 1 beta	Rattus norvegicus	49-57