PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20736346-4 2010 The goal of this study was to determine whether the natural compound psoralidin alters EGFR-mediated signaling resulting in the inhibition of prostate cancer growth. psoralidin 69-79 epidermal growth factor receptor Mus musculus 87-91 20736346-6 2010 Treatment with psoralidin, however, inhibited both constitutive and EGF-induced EGFR activation and simultaneously triggered SAPK signaling, resulting in the induction of apoptosis in AIPC cells. psoralidin 15-25 epidermal growth factor receptor Mus musculus 80-84 20736346-7 2010 In addition, psoralidin downregulated EGFR-regulated MAPK signaling and inhibited cell proliferation in AIPC cells. psoralidin 13-23 epidermal growth factor receptor Mus musculus 38-42 20736346-10 2010 Our studies suggest that psoralidin may be a potent therapeutic agent that modulates EGFR-mediated key epigenetic events in AIPC. psoralidin 25-35 epidermal growth factor receptor Mus musculus 85-89